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OPENSEQ.org

MYOTACTA

Genes: A B A+B
Length: 99 377 469
Sequences: 10020 13012 152
Seq/Len: 101.21 34.51 0.32
MirrorTree (Pazo et al. 2001) 0.02
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.

Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.14 0.04 0.02
2 0.16 0.04 0.02
5 0.18 0.05 0.03
10 0.19 0.06 0.05
20 0.19 0.06 0.07
100 0.20 0.12 0.19
0.22 0.17 0.32
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!

GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution.
Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
71_A 101_E 1.18 0.24 0.00
83_G 311_I 1.17 0.24 0.00
35_W 344_G 1.08 0.20 0.00
34_F 221_V 1.05 0.18 0.00
85_T 197_E 1.03 0.17 0.00
84_V 287_C 1.00 0.16 0.00
35_W 184_G 0.99 0.16 0.00
37_R 256_R 0.99 0.16 0.00
69_K 10_L 0.97 0.15 0.00
19_V 221_V 0.97 0.15 0.00
35_W 158_G 0.97 0.15 0.00
19_V 188_T 0.95 0.15 0.00
85_T 87_I 0.93 0.14 0.00
38_N 194_I 0.93 0.14 0.00
35_W 15_G 0.91 0.13 0.00
78_A 183_A 0.90 0.13 0.00
13_V 367_A 0.89 0.13 0.00
35_W 303_G 0.89 0.13 0.00
74_Y 304_G 0.89 0.13 0.00
78_A 320_T 0.89 0.12 0.00
34_F 276_I 0.88 0.12 0.00
91_L 304_G 0.88 0.12 0.00
84_V 221_V 0.87 0.12 0.00
4_F 191_L 0.86 0.12 0.00
18_S 300_V 0.86 0.12 0.00
48_R 278_E 0.85 0.12 0.00
83_G 256_R 0.85 0.12 0.00
72_G 184_G 0.85 0.12 0.00
74_Y 344_G 0.85 0.11 0.00
85_T 69_L 0.85 0.11 0.00
63_I 23_F 0.84 0.11 0.00
93_V 154_V 0.84 0.11 0.00
74_Y 294_D 0.83 0.11 0.00
31_P 344_G 0.82 0.11 0.00
21_L 214_I 0.81 0.10 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

ID Seq/Len Name Options I_Prob Status
2007 0.32 MYOTACTA Δgene:(1, ∞) A:(1E-80, 8) B:(1E-04, 8) msa: Jackhmmer (2015_03) 0.00 Done - Shared
2006 0.18 MYOTACTA Δgene:(1, ∞) A:(1E-80, 8) B:(1E-80, 8) msa: Jackhmmer (2015_03) Killed - Shared
2005 0.51 MYOTACTA Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_03) 0.00 Done - Shared
2004 0.15 MYOTACTA Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_03) Killed - Shared

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