May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
MYOTACTA
Genes: A B A+B
Length: 99 377 471
Sequences: 18397 2458 239
Seq/Len: 185.83 6.52 0.51
MirrorTree (Pazo et al. 2001) 0.04
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.
Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.17 0.04 0.02
2 0.19 0.05 0.03
5 0.21 0.05 0.05
10 0.21 0.06 0.09
20 0.22 0.07 0.14
100 0.24 0.10 0.36
∞ 0.26 0.17 0.50
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!
GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution. 		Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
27_A 105_T 1.23 0.36 0.00
35_W 158_G 1.12 0.29 0.00
71_A 214_I 1.10 0.28 0.00
76_V 299_N 1.08 0.27 0.00
65_D 187_L 1.02 0.23 0.00
91_L 308_Y 1.01 0.22 0.00
19_V 220_Y 1.00 0.22 0.00
33_L 348_L 0.98 0.21 0.00
23_C 131_V 0.97 0.20 0.00
93_V 284_I 0.95 0.20 0.00
72_G 183_A 0.95 0.19 0.00
19_V 307_M 0.95 0.19 0.00
35_W 303_G 0.93 0.18 0.00
60_T 295_L 0.91 0.17 0.00
63_I 228_E 0.91 0.17 0.00
37_R 305_T 0.90 0.17 0.00
78_A 365_D 0.90 0.17 0.00
42_V 11_V 0.89 0.17 0.00
21_L 255_E 0.88 0.16 0.00
19_V 107_L 0.88 0.16 0.00
15_E 11_V 0.88 0.16 0.00
74_Y 158_G 0.87 0.16 0.00
40_E 90_H 0.86 0.15 0.00
17_D 56_V 0.86 0.15 0.00
26_S 69_L 0.86 0.15 0.00
33_L 24_A 0.85 0.15 0.00
91_L 294_D 0.85 0.15 0.00
62_L 143_S 0.84 0.15 0.00
63_I 372_V 0.84 0.14 0.00
91_L 168_Y 0.84 0.14 0.00
33_L 278_E 0.83 0.14 0.00
48_R 37_V 0.81 0.13 0.00
86_T 94_N 0.81 0.13 0.00
47_D 322_L 0.80 0.13 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)
ID Seq/Len Name Options I_Prob Status
2007 0.32 MYOTACTA Δgene:(1, ∞) A:(1E-80, 8) B:(1E-04, 8) msa: Jackhmmer (2015_03) 0.00 Done - Shared
2006 0.18 MYOTACTA Δgene:(1, ∞) A:(1E-80, 8) B:(1E-80, 8) msa: Jackhmmer (2015_03) Killed - Shared
2005 0.51 MYOTACTA Δgene:(1, ∞) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_03) 0.00 Done - Shared
2004 0.15 MYOTACTA Δgene:(1, 20) A:(1E-20, 8) B:(1E-20, 8) msa: Jackhmmer (2015_03) Killed - Shared
Page generated in 0.3662 seconds.