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OPENSEQ.org

L31 - S19
UniProt: Q5SJE1 - Q5SHP2
Length: 164
Sequences: 981
Seq/Len: 6.33
I_Prob: 1.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2d4 3v2eS 3v2f4Contact Map
2j002j00S 2j014 2j02S 2j034Contact Map
4juw4juwS 4jux4Contact Map
3uyd3uydV 3uye4 3uyfV 3uyg4Contact Map
3ohc3ohcS 3ohdS 3ohj4 3ohk4Contact Map
3knh3knhS 3kni4 3knjS 3knk4Contact Map
3ohy3ohyS 3ohz4 3oi0S 3oi14Contact Map
3f1e3f1eS 3f1f4 3f1gS 3f1h4Contact Map
3v223v22S 3v234 3v24S 3v254Contact Map
3uz63uz6V 3uz7V 3uz84 3uz94Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
56_V 45_V 2.79 1.00
60_Q 43_E 1.40 0.90
62_R 39_T 1.38 0.89
65_D 52_Y 1.37 0.89
49_F 45_V 1.29 0.85
53_E 65_N 1.25 0.83
55_R 28_K 1.11 0.72
58_R 76_P 1.02 0.62
65_D 43_E 0.99 0.59
57_E 61_Y 0.93 0.52
52_T 65_N 0.91 0.48
48_R 88_K 0.90 0.47
11_P 52_Y 0.87 0.44
35_V 20_L 0.84 0.40
51_D 43_E 0.83 0.39
50_V 84_G 0.82 0.37
43_Y 26_G 0.80 0.35
28_K 40_I 0.80 0.34
34_E 29_R 0.80 0.34
53_E 53_N 0.79 0.34
27_T 2_P 0.77 0.31
53_E 57_H 0.76 0.30
34_E 65_N 0.76 0.29
66_S 62_I 0.74 0.28
53_E 64_E 0.74 0.28
65_D 88_K 0.70 0.23
12_A 44_M 0.69 0.22
43_Y 57_H 0.69 0.22
61_R 51_V 0.68 0.21
8_K 26_G 0.68 0.21
15_I 44_M 0.67 0.20
48_R 79_T 0.67 0.20
16_C 71_L 0.65 0.18
34_E 67_V 0.65 0.18
60_Q 65_N 0.65 0.18
8_K 16_L 0.65 0.18
10_V 75_A 0.64 0.18
51_D 11_V 0.64 0.17
53_E 58_V 0.64 0.17
62_R 15_L 0.63 0.17
12_A 75_A 0.63 0.17
52_T 14_H 0.63 0.16
52_T 62_I 0.63 0.16
55_R 32_K 0.61 0.15
47_Q 67_V 0.60 0.14
52_T 21_E 0.60 0.14
57_E 86_E 0.60 0.14
18_C 63_T 0.60 0.14
61_R 2_P 0.59 0.14
24_T 47_H 0.59 0.13
56_V 67_V 0.59 0.13
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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