May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
4HEA_K - 4HEA_M
UniProt: Q56226 - Q56228 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 564
Sequences: 3125
Seq/Len: 5.66
I_Prob: 0.34
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaMU:LT:NV:KSContact Map
4he8GM:FL:IN:EKContact Map
3rkoCM:BL:DN:GKContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
58_L 392_A 1.23 0.34
44_G 177_L 1.14 0.28
30_S 338_T 1.07 0.23
49_Y 376_G 0.93 0.14
14_G 421_G 0.92 0.14
15_V 366_V 0.92 0.14
69_A 296_A 0.91 0.14
40_L 132_M 0.91 0.13
14_G 376_G 0.91 0.13
40_L 433_A 0.90 0.13
56_A 399_V 0.89 0.12
47_R 114_D 0.87 0.11
58_L 247_P 0.86 0.11
62_A 299_G 0.84 0.10
38_A 301_F 0.80 0.09
39_N 95_F 0.80 0.09
48_A 109_L 0.79 0.08
58_L 418_G 0.79 0.08
34_M 210_L 0.79 0.08
25_I 92_E 0.79 0.08
27_V 302_S 0.78 0.08
29_L 159_M 0.78 0.08
29_L 161_A 0.78 0.08
19_L 114_D 0.78 0.08
59_M 108_G 0.78 0.08
14_G 265_A 0.77 0.08
79_F 166_A 0.77 0.08
87_V 143_R 0.77 0.08
34_M 277_A 0.76 0.07
48_A 304_T 0.76 0.07
12_A 342_G 0.76 0.07
74_L 154_V 0.76 0.07
56_A 161_A 0.76 0.07
90_L 295_V 0.75 0.07
37_A 180_L 0.75 0.07
39_N 150_L 0.74 0.07
76_V 314_L 0.74 0.07
26_L 224_S 0.73 0.07
16_Y 108_G 0.73 0.07
86_A 307_G 0.73 0.07
42_L 160_L 0.73 0.07
60_V 317_A 0.73 0.07
17_G 103_E 0.73 0.07
14_G 264_A 0.72 0.06
14_G 332_L 0.72 0.06
19_L 210_L 0.72 0.06
88_D 394_L 0.72 0.06
23_T 316_A 0.72 0.06
69_A 291_S 0.72 0.06
42_L 391_L 0.72 0.06
87_V 336_T 0.71 0.06
41_S 198_A 0.71 0.06
9_L 199_L 0.71 0.06
58_L 249_A 0.71 0.06
70_V 366_V 0.71 0.06
61_I 238_V 0.71 0.06
63_V 298_L 0.70 0.06
41_S 371_L 0.70 0.06
75_I 276_F 0.70 0.06
12_A 205_T 0.70 0.06
72_L 292_H 0.69 0.06
59_M 264_A 0.69 0.06
56_A 413_T 0.69 0.06
59_M 104_G 0.69 0.06
90_L 356_A 0.69 0.06
52_D 132_M 0.69 0.06
60_V 252_G 0.69 0.06
56_A 116_L 0.69 0.06
91_S 410_F 0.69 0.05
55_V 81_T 0.68 0.05
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.4286 seconds.