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OPENSEQ.org
4HEA_9 - 4HEA_N
UniProt: Q56224 - Q56229 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 609
Sequences: 1521
Seq/Len: 2.67
I_Prob: 0.03
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaNV:MU:LT:9O:9OContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
62_A 320_P 1.13 0.03
122_A 193_H 1.05 0.02
58_L 185_F 0.91 0.01
94_N 152_A 0.85 0.01
105_E 242_V 0.83 0.01
20_K 268_Y 0.82 0.01
95_M 149_Y 0.80 0.01
67_A 215_V 0.78 0.01
115_L 362_V 0.76 0.01
105_E 246_L 0.76 0.01
130_V 266_A 0.75 0.01
122_A 344_G 0.75 0.01
120_E 193_H 0.75 0.01
117_Y 268_Y 0.74 0.01
17_L 379_G 0.74 0.01
26_Y 333_L 0.74 0.01
67_A 175_A 0.72 0.01
113_I 317_R 0.72 0.01
70_V 148_L 0.71 0.01
111_G 104_L 0.71 0.01
97_R 152_A 0.70 0.01
33_L 324_L 0.70 0.01
113_I 104_L 0.70 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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