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OPENSEQ.org
4HEA_3 - 4HEA_J
UniProt: Q56223 - Q56225 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 959
Sequences: 1257
Seq/Len: 1.45
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea3D:JR:9OContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
601_V 56_V 1.15 0.00
390_L 20_V 1.15 0.00
495_E 15_S 1.06 0.00
285_V 28_A 1.02 0.00
521_A 13_L 1.01 0.00
644_L 39_L 1.00 0.00
565_Y 127_L 1.00 0.00
399_L 13_L 0.98 0.00
458_L 56_V 0.92 0.00
318_V 40_A 0.92 0.00
525_A 145_L 0.91 0.00
614_L 8_A 0.88 0.00
476_I 131_L 0.88 0.00
396_A 110_G 0.86 0.00
368_H 9_L 0.84 0.00
521_A 56_V 0.84 0.00
614_L 141_A 0.84 0.00
254_T 22_L 0.83 0.00
568_Y 141_A 0.83 0.00
393_A 16_G 0.82 0.00
312_R 28_A 0.81 0.00
638_L 63_I 0.81 0.00
341_V 41_G 0.80 0.00
451_F 73_L 0.80 0.00
261_V 14_L 0.79 0.00
582_F 41_G 0.78 0.00
383_P 136_L 0.78 0.00
451_F 85_P 0.78 0.00
573_P 29_A 0.77 0.00
369_L 17_V 0.76 0.00
272_G 13_L 0.76 0.00
524_L 13_L 0.75 0.00
656_L 124_P 0.75 0.00
396_A 101_A 0.74 0.00
568_Y 144_F 0.74 0.00
310_L 46_L 0.74 0.00
323_E 119_L 0.73 0.00
254_T 20_V 0.73 0.00
665_K 118_D 0.73 0.00
267_A 52_G 0.73 0.00
448_M 151_V 0.72 0.00
326_F 149_A 0.72 0.00
311_V 151_V 0.72 0.00
334_K 22_L 0.72 0.00
314_E 56_V 0.72 0.00
526_E 151_V 0.71 0.00
531_K 52_G 0.71 0.00
361_A 52_G 0.70 0.00
307_K 63_I 0.70 0.00
333_L 5_E 0.70 0.00
11_V 79_G 0.70 0.00
611_R 51_L 0.70 0.00
658_L 95_L 0.69 0.00
331_E 14_L 0.69 0.00
594_A 23_R 0.69 0.00
668_K 102_G 0.69 0.00
494_K 56_V 0.69 0.00
412_R 68_L 0.68 0.00
365_K 141_A 0.68 0.00
320_A 149_A 0.68 0.00
418_R 22_L 0.68 0.00
613_H 46_L 0.68 0.00
269_T 63_I 0.67 0.00
415_E 133_G 0.67 0.00
450_L 137_F 0.67 0.00
446_D 150_T 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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