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OPENSEQ.org
4HEA_1 - 4HEA_H
UniProt: Q56222 - Q60019 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 803
Sequences: 1103
Seq/Len: 1.50
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea1B:HQContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
260_R 204_L 1.18 0.00
280_A 258_L 1.03 0.00
54_I 105_P 0.93 0.00
120_L 100_I 0.88 0.00
422_L 285_F 0.88 0.00
90_I 201_P 0.85 0.00
231_M 285_F 0.83 0.00
254_I 205_V 0.82 0.00
274_E 252_F 0.82 0.00
53_V 150_L 0.82 0.00
127_A 164_L 0.80 0.00
197_A 226_Q 0.80 0.00
57_V 81_L 0.79 0.00
107_L 242_A 0.78 0.00
55_E 280_F 0.77 0.00
54_I 79_R 0.74 0.00
170_D 254_T 0.73 0.00
236_D 208_I 0.73 0.00
317_Q 40_A 0.73 0.00
74_L 234_T 0.73 0.00
285_E 289_F 0.72 0.00
339_D 243_L 0.72 0.00
34_R 280_F 0.72 0.00
91_C 32_T 0.72 0.00
264_Y 126_F 0.72 0.00
226_S 217_T 0.71 0.00
54_I 179_S 0.71 0.00
189_M 137_F 0.71 0.00
134_V 88_I 0.69 0.00
71_P 125_L 0.69 0.00
91_C 122_I 0.69 0.00
121_A 144_G 0.69 0.00
49_T 316_L 0.69 0.00
110_V 152_S 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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