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OPENSEQ.org

4HEA_1 - 4HEA_L
UniProt: Q56222 - Q56227 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 1044
Sequences: 1286
Seq/Len: 1.27
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea1B:LT:MU:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
388_E 188_L 0.87 0.00
313_Y 67_L 0.87 0.00
54_I 148_N 0.85 0.00
251_L 125_P 0.82 0.00
225_A 259_L 0.79 0.00
414_L 128_F 0.75 0.00
268_M 349_V 0.73 0.00
118_M 172_G 0.72 0.00
290_I 372_A 0.71 0.00
173_V 121_A 0.70 0.00
273_R 256_S 0.70 0.00
378_Q 184_S 0.70 0.00
263_V 373_L 0.70 0.00
52_E 202_L 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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