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OPENSEQ.org

4HEA_1 - 4HEA_3
UniProt: Q56222 - Q56223 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 1221
Sequences: 1991
Seq/Len: 1.78
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3iam3C:1A:9GContact Map
3i9v3C:1A:9GContact Map
3ias3UCL:1SJA:9YGPContact Map
3m9s3C:1A:9GContact Map
2fug3CLU:1SAJ:9YPGContact Map
4hea3D:1B:9OContact Map
2ybb3:1:8Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
30_D 480_L 0.82 0.00
173_V 566_A 0.81 0.00
132_I 393_A 0.80 0.00
51_D 492_K 0.80 0.00
52_E 304_N 0.79 0.00
382_K 341_V 0.78 0.00
285_E 293_A 0.75 0.00
57_V 321_T 0.74 0.00
115_I 574_E 0.73 0.00
49_T 331_E 0.71 0.00
274_E 306_L 0.70 0.00
235_A 392_Q 0.68 0.00
370_L 392_Q 0.68 0.00
90_I 567_Y 0.65 0.00
260_R 323_E 0.65 0.00
308_D 308_T 0.65 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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