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OPENSEQ.org

4HEA_1 - 4HEA_4
UniProt: Q56222 - Q56220 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 847
Sequences: 1244
Seq/Len: 1.55
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3ias1SJA:4DVMContact Map
3i9v1A:4DContact Map
2fug1SAJ:4VMDContact Map
3m9s1A:4DContact Map
4hea1B:4EContact Map
3iam1A:4DContact Map
2ybb1:4Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
336_S 52_V 0.96 0.00
107_L 291_K 0.82 0.00
394_I 193_L 0.80 0.00
171_L 159_L 0.80 0.00
284_L 261_T 0.74 0.00
276_I 187_V 0.73 0.00
346_R 194_L 0.72 0.00
50_P 244_V 0.71 0.00
192_L 106_G 0.70 0.00
384_V 47_L 0.69 0.00
232_E 357_I 0.69 0.00
115_I 234_L 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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