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OPENSEQ.org

4HEA_1 - 4HEA_6
UniProt: Q56222 - Q56218 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 619
Sequences: 1190
Seq/Len: 2.10
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3ias1SJA:6FOXContact Map
3i9v1A:6FContact Map
2fug1SAJ:6FOXContact Map
3m9s1A:6FContact Map
4hea1B:6GContact Map
3iam1A:6FContact Map
2ybb1:6Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
300_L 77_V 0.91 0.00
51_D 130_V 0.81 0.00
275_L 148_I 0.78 0.00
57_V 130_V 0.76 0.00
389_A 60_L 0.75 0.00
274_E 77_V 0.74 0.00
122_G 135_V 0.72 0.00
142_A 107_S 0.70 0.00
54_I 63_F 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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