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OPENSEQ.org
4HEA_2 - 4HEA_9
UniProt: Q56221 - Q56224 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 363
Sequences: 1095
Seq/Len: 3.56
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3ias9YGP:2TKB:3UCLContact Map
3i9v9G:2B:3CContact Map
2fug9YPG:2TKB:3CLUContact Map
3m9s9G:2B:3CContact Map
3iam9G:2B:3CContact Map
4hea9O:2C:3DContact Map
2ybb8:2:3Contact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
65_S 138_V 0.87 0.00
93_A 30_P 0.80 0.00
150_L 74_E 0.79 0.00
59_E 115_L 0.74 0.00
78_Y 74_E 0.73 0.00
118_S 119_F 0.66 0.00
125_L 35_P 0.64 0.00
92_G 107_A 0.63 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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