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OPENSEQ.org
4HEA_2 - 4HEA_5
UniProt: Q56221 - Q56219 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 388
Sequences: 1262
Seq/Len: 4.08
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3ias5NEW:2TKB:4DVMContact Map
3i9v5E:2B:4DContact Map
2fug5NEW:2TKB:4VMDContact Map
3m9s5E:2B:4DContact Map
3iam5E:2B:4DContact Map
4hea5F:2C:4EContact Map
2ybb5:2:4Contact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
87_S 108_W 0.90 0.00
134_I 124_I 0.83 0.00
154_L 52_I 0.80 0.00
136_V 85_G 0.78 0.00
121_K 141_L 0.72 0.00
117_F 101_L 0.72 0.00
154_L 29_L 0.71 0.00
148_A 128_G 0.71 0.00
80_L 114_L 0.68 0.00
135_Q 66_E 0.66 0.00
63_V 92_V 0.66 0.00
141_Y 124_I 0.65 0.00
97_W 42_K 0.65 0.00
82_V 144_H 0.64 0.00
125_L 67_R 0.64 0.00
100_L 127_E 0.64 0.00
28_M 110_S 0.64 0.00
131_A 108_W 0.64 0.00
80_L 68_F 0.63 0.00
93_A 131_D 0.63 0.00
151_E 27_V 0.62 0.00
95_E 88_F 0.62 0.00
134_I 52_I 0.61 0.00
154_L 110_S 0.61 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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