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OPENSEQ.org
4HEA_2 - 4HEA_A
UniProt: Q56221 - Q56217 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 300
Sequences: 1052
Seq/Len: 3.80
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea2C:APContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
153_L 111_W 0.91 0.00
152_A 30_L 0.89 0.00
82_V 112_W 0.89 0.00
80_L 37_G 0.84 0.00
145_V 44_Y 0.81 0.00
126_G 93_F 0.81 0.00
99_Y 116_M 0.80 0.00
117_F 117_R 0.80 0.00
156_G 30_L 0.79 0.00
62_G 66_M 0.79 0.00
80_L 23_A 0.79 0.00
136_V 19_F 0.79 0.00
77_K 23_A 0.79 0.00
79_H 107_F 0.79 0.00
151_E 43_P 0.78 0.00
117_F 108_L 0.77 0.00
28_M 32_G 0.76 0.00
115_G 26_L 0.76 0.00
72_F 113_K 0.76 0.00
89_K 70_L 0.76 0.00
24_R 62_Y 0.74 0.00
157_L 33_P 0.74 0.00
87_S 41_L 0.73 0.00
93_A 19_F 0.73 0.00
139_E 33_P 0.73 0.00
79_H 92_G 0.72 0.00
65_S 89_G 0.72 0.00
149_R 20_I 0.71 0.00
110_E 15_G 0.70 0.00
86_L 41_L 0.69 0.00
119_V 11_L 0.69 0.00
80_L 89_G 0.69 0.00
120_Q 85_A 0.69 0.00
140_P 26_L 0.69 0.00
116_L 56_R 0.69 0.00
99_Y 70_L 0.69 0.00
94_E 18_L 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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