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OPENSEQ.org

4HEA_4 - 4HEA_M
UniProt: Q56220 - Q56228 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 878
Sequences: 1559
Seq/Len: 1.84
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea4E:MU:LT:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
126_L 112_A 0.99 0.00
106_G 259_L 0.96 0.00
107_A 399_V 0.88 0.00
232_L 363_L 0.88 0.00
109_V 344_Y 0.83 0.00
201_I 78_I 0.82 0.00
244_V 363_L 0.81 0.00
134_G 91_V 0.79 0.00
48_S 323_G 0.75 0.00
192_K 161_A 0.73 0.00
103_K 394_L 0.73 0.00
294_L 120_V 0.71 0.00
103_K 11_V 0.71 0.00
280_I 441_L 0.70 0.00
342_V 186_Q 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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