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OPENSEQ.org

4HEA_4 - 4HEA_L
UniProt: Q56220 - Q56227 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 1015
Sequences: 1562
Seq/Len: 1.58
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaLT:4E:MU:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
201_I 336_S 1.20 0.01
220_G 455_L 0.91 0.00
134_G 369_G 0.84 0.00
149_A 80_V 0.83 0.00
149_A 286_F 0.81 0.00
168_F 136_L 0.79 0.00
193_L 352_M 0.79 0.00
210_E 275_L 0.77 0.00
221_V 16_L 0.76 0.00
261_T 379_L 0.76 0.00
397_I 453_S 0.76 0.00
241_A 259_L 0.76 0.00
222_G 47_L 0.73 0.00
290_I 69_L 0.73 0.00
52_V 171_L 0.72 0.00
118_V 304_G 0.70 0.00
163_V 282_A 0.70 0.00
112_R 90_Y 0.70 0.00
98_A 67_L 0.70 0.00
258_E 176_L 0.70 0.00
150_F 184_S 0.70 0.00
97_Y 369_G 0.69 0.00
93_H 221_P 0.69 0.00
89_H 393_L 0.68 0.00
233_G 339_V 0.68 0.00
222_G 40_S 0.68 0.00
171_N 382_F 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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