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OPENSEQ.org

4HEA_4 - 4HEA_9
UniProt: Q56220 - Q56224 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 591
Sequences: 1603
Seq/Len: 3.01
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3ias4DVM:9YGP:3UCLContact Map
3i9v4D:9G:3CContact Map
3m9s4D:9G:3CContact Map
2fug4VMD:9YPG:3CLUContact Map
4hea4E:9O:3DContact Map
3iam4D:9G:3CContact Map
2ybb4:8:3Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
59_I 113_I 1.01 0.01
180_E 36_R 0.86 0.01
206_A 12_I 0.85 0.01
171_N 103_L 0.80 0.01
203_E 19_S 0.78 0.00
97_Y 103_L 0.72 0.00
242_S 116_G 0.71 0.00
174_R 106_E 0.69 0.00
194_L 90_V 0.65 0.00
73_R 67_A 0.64 0.00
178_V 66_Y 0.63 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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