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OPENSEQ.org
4HEA_5 - 4HEA_M
UniProt: Q56219 - Q56228 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 676
Sequences: 1521
Seq/Len: 2.54
I_Prob: 0.02
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaMU:LT:NV:5FContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
54_G 325_L 1.11 0.02
121_L 432_F 1.06 0.01
73_E 109_L 0.91 0.01
97_E 445_V 0.88 0.01
101_L 11_V 0.86 0.01
90_V 379_L 0.84 0.01
133_R 152_T 0.83 0.01
102_P 146_Y 0.83 0.01
102_P 370_G 0.83 0.01
119_Y 439_A 0.82 0.01
97_E 74_F 0.79 0.01
95_P 12_F 0.78 0.01
135_I 296_A 0.71 0.01
146_L 302_S 0.71 0.01
29_L 434_L 0.71 0.01
146_L 367_G 0.71 0.01
54_G 345_R 0.70 0.01
92_V 112_A 0.70 0.01
104_V 132_M 0.70 0.01
107_L 180_L 0.70 0.01
124_I 356_A 0.70 0.01
39_A 11_V 0.69 0.01
54_G 242_F 0.69 0.01
94_V 203_I 0.69 0.01
74_L 166_A 0.69 0.01
135_I 311_G 0.69 0.01
120_D 274_V 0.68 0.01
49_L 290_L 0.68 0.01
34_F 81_T 0.68 0.01
50_A 399_V 0.68 0.01
48_F 125_A 0.68 0.01
139_E 299_G 0.68 0.01
103_T 283_T 0.68 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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