May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
4HEA_5 - 4HEA_L
UniProt: Q56219 - Q56227 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 813
Sequences: 1534
Seq/Len: 2.07
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaLT:MU:NV:5FContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
121_L 392_T 1.02 0.00
124_I 59_W 0.95 0.00
119_Y 187_E 0.87 0.00
103_T 567_L 0.83 0.00
34_F 360_P 0.81 0.00
131_D 260_Y 0.80 0.00
120_D 104_F 0.80 0.00
90_V 272_V 0.79 0.00
111_A 317_V 0.78 0.00
108_W 101_Y 0.78 0.00
120_D 223_M 0.77 0.00
41_Y 111_F 0.77 0.00
141_L 144_F 0.77 0.00
103_T 378_L 0.77 0.00
102_P 99_P 0.76 0.00
54_G 142_I 0.74 0.00
111_A 112_I 0.74 0.00
84_D 339_V 0.74 0.00
124_I 16_L 0.74 0.00
88_F 408_L 0.72 0.00
101_L 438_A 0.71 0.00
37_E 336_S 0.71 0.00
90_V 178_A 0.70 0.00
88_F 89_V 0.70 0.00
119_Y 211_L 0.70 0.00
34_F 264_P 0.70 0.00
41_Y 339_V 0.70 0.00
56_D 151_Y 0.69 0.00
90_V 376_L 0.69 0.00
88_F 595_L 0.69 0.00
90_V 273_V 0.69 0.00
92_V 454_V 0.69 0.00
54_G 175_I 0.69 0.00
103_T 447_H 0.69 0.00
54_G 160_I 0.69 0.00
122_F 6_T 0.69 0.00
108_W 392_T 0.68 0.00
29_L 503_L 0.68 0.00
104_V 508_G 0.68 0.00
137_T 347_Q 0.68 0.00
34_F 252_L 0.68 0.00
30_P 207_L 0.68 0.00
101_L 82_G 0.67 0.00
77_L 285_A 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.4617 seconds.