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OPENSEQ.org

4HEA_6 - 4HEA_M
UniProt: Q56218 - Q56228 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 650
Sequences: 1502
Seq/Len: 2.44
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaMU:LT:6G:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
135_V 112_A 0.89 0.00
106_I 87_L 0.82 0.00
155_Q 376_G 0.78 0.00
52_A 175_F 0.77 0.00
61_A 415_W 0.77 0.00
70_A 402_S 0.73 0.00
70_A 283_T 0.73 0.00
135_V 342_G 0.73 0.00
148_I 167_R 0.72 0.00
151_V 165_G 0.71 0.00
51_M 164_L 0.71 0.00
154_L 203_I 0.70 0.00
148_I 370_G 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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