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OPENSEQ.org

4HEA_6 - 4HEA_L
UniProt: Q56218 - Q56227 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 787
Sequences: 1547
Seq/Len: 2.04
I_Prob: 0.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4heaLT:6G:MU:NVContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
103_K 260_Y 0.86 0.00
150_A 336_S 0.83 0.00
100_P 251_Y 0.81 0.00
106_I 277_T 0.80 0.00
148_I 323_F 0.80 0.00
54_T 220_I 0.77 0.00
148_I 99_P 0.75 0.00
80_V 305_Y 0.74 0.00
75_A 113_A 0.73 0.00
150_A 271_A 0.72 0.00
88_M 277_T 0.72 0.00
114_S 169_F 0.71 0.00
144_P 295_V 0.71 0.00
36_L 332_L 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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