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OPENSEQ.org
4HEA_6 - 4HEA_J
UniProt: Q56218 - Q56225 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 357
Sequences: 1104
Seq/Len: 3.48
I_Prob: 0.07
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4hea6G:JRContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
25_E 51_L 1.14 0.07
63_F 102_G 1.13 0.07
131_V 75_F 1.11 0.07
147_L 49_R 1.02 0.05
122_A 62_A 1.00 0.05
149_Y 137_F 0.98 0.05
31_G 44_V 0.98 0.05
94_R 43_Y 0.94 0.04
85_S 43_Y 0.92 0.04
106_I 24_N 0.92 0.04
117_M 74_L 0.92 0.04
67_V 131_L 0.90 0.04
77_V 15_S 0.89 0.03
154_L 63_I 0.88 0.03
135_V 14_L 0.85 0.03
158_V 133_G 0.84 0.03
22_T 21_T 0.83 0.03
85_S 140_L 0.82 0.03
117_M 25_A 0.82 0.03
39_A 32_L 0.80 0.03
107_S 47_D 0.80 0.03
107_S 49_R 0.79 0.02
74_Q 128_G 0.78 0.02
58_N 7_L 0.78 0.02
95_V 70_V 0.77 0.02
86_K 29_A 0.77 0.02
151_V 57_I 0.76 0.02
81_A 150_T 0.76 0.02
54_T 37_L 0.76 0.02
125_Q 62_A 0.75 0.02
147_L 16_G 0.74 0.02
92_M 13_L 0.73 0.02
91_V 63_I 0.73 0.02
36_L 130_L 0.73 0.02
145_E 52_G 0.72 0.02
153_Q 43_Y 0.72 0.02
110_A 67_F 0.72 0.02
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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