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OPENSEQ.org

S11 - S19
UniProt: P80376 - Q5SHP2
Length: 222
Sequences: 1124
Seq/Len: 5.20
I_Prob: 0.40
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2vqe2vqeKSContact Map
3v2c3v2cKS 3v2eKSContact Map
2uub2uubKSContact Map
2j002j00KS 2j02KSContact Map
3t1y3t1yKSContact Map
4juw4juwKSContact Map
2uua2uuaKSContact Map
4b3m4b3mKSContact Map
2uxc2uxcKSContact Map
4kix4kiyKS 4kj0KS 4kj2KS 4kj4KSContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
83_I 44_M 1.26 0.40
95_I 81_R 1.11 0.28
7_K 45_V 1.03 0.22
107_S 44_M 0.97 0.18
103_L 61_Y 0.94 0.17
83_I 52_Y 0.90 0.14
16_S 88_K 0.89 0.14
72_A 43_E 0.84 0.12
93_Q 80_Y 0.84 0.11
7_K 65_N 0.83 0.11
8_K 87_A 0.82 0.10
125_F 67_V 0.81 0.10
18_R 53_N 0.80 0.10
10_V 5_L 0.80 0.10
85_R 69_H 0.80 0.10
63_L 87_A 0.80 0.10
63_L 86_E 0.80 0.10
21_I 6_K 0.79 0.10
114_V 26_G 0.79 0.09
34_D 27_E 0.78 0.09
2_A 62_I 0.77 0.09
59_Y 81_R 0.77 0.09
31_T 63_T 0.77 0.08
2_A 27_E 0.76 0.08
115_P 69_H 0.76 0.08
4_K 26_G 0.76 0.08
105_V 22_L 0.76 0.08
22_H 11_V 0.75 0.08
59_Y 6_K 0.75 0.08
12_R 86_E 0.75 0.08
24_S 10_F 0.75 0.08
9_K 84_G 0.74 0.08
97_A 27_E 0.74 0.07
97_A 85_K 0.74 0.07
5_P 26_G 0.73 0.07
9_K 41_V 0.72 0.07
15_A 53_N 0.72 0.07
114_V 20_L 0.72 0.07
65_A 19_V 0.72 0.07
4_K 85_K 0.72 0.07
14_V 57_H 0.71 0.07
118_G 78_R 0.71 0.07
12_R 17_E 0.71 0.07
122_K 70_K 0.71 0.07
99_Q 66_M 0.71 0.07
84_V 56_Q 0.70 0.07
106_K 29_R 0.70 0.06
93_Q 87_A 0.69 0.06
13_Q 16_L 0.69 0.06
87_T 83_H 0.69 0.06
32_I 49_I 0.69 0.06
6_S 87_A 0.69 0.06
98_L 57_H 0.68 0.06
59_Y 40_I 0.68 0.06
35_P 29_R 0.68 0.06
39_P 67_V 0.68 0.06
5_P 85_K 0.68 0.06
2_A 88_K 0.67 0.06
4_K 43_E 0.67 0.06
5_P 23_N 0.67 0.06
104_Q 44_M 0.66 0.05
6_S 23_N 0.66 0.05
63_L 2_P 0.66 0.05
78_Q 62_I 0.66 0.05
6_S 26_G 0.66 0.05
100_A 56_Q 0.66 0.05
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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