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OPENSEQ.org

L32 - S19
UniProt: P80339 - Q5SHP2
Length: 153
Sequences: 726
Seq/Len: 4.94
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2d5 3v2eS 3v2f5Contact Map
2j002j00S 2j015 2j02S 2j035Contact Map
4juw4juwS 4jux5Contact Map
4kix4kix0 4kiyS 4kiz0 4kj0S 4kj10 4kj2S 4kj30 4kj4SContact Map
4kj54kj50 4kj6S 4kj70 4kj8S 4kj90 4kjaS 4kjb0 4kjcSContact Map
3uyd3uydV 3uye5 3uyfV 3uyg5Contact Map
4gd13r8s0 3r8t0 4gd1S 4gd2SContact Map
3knh3knhS 3kni5 3knjS 3knk5Contact Map
3ohc3ohcS 3ohdS 3ohj5 3ohk5Contact Map
3ohy3ohyS 3ohz5 3oi0S 3oi15Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
45_V 61_Y 0.93 0.01
37_K 88_K 0.92 0.01
35_E 64_E 0.90 0.01
54_G 67_V 0.87 0.01
24_A 37_R 0.85 0.01
27_P 62_I 0.84 0.01
8_K 43_E 0.83 0.01
18_A 45_V 0.81 0.01
51_Y 62_I 0.80 0.01
59_E 58_V 0.79 0.01
13_K 11_V 0.79 0.01
14_A 44_M 0.78 0.01
15_R 40_I 0.77 0.01
38_A 59_P 0.76 0.01
4_H 56_Q 0.74 0.01
10_K 87_A 0.73 0.01
6_V 76_P 0.72 0.01
23_H 53_N 0.72 0.01
45_V 52_Y 0.72 0.01
34_P 49_I 0.70 0.01
44_T 19_V 0.70 0.01
26_T 61_Y 0.69 0.01
44_T 16_L 0.69 0.01
27_P 52_Y 0.69 0.01
42_P 56_Q 0.69 0.01
13_K 65_N 0.69 0.01
25_L 12_D 0.68 0.01
42_P 60_V 0.68 0.01
35_E 61_Y 0.67 0.00
10_K 82_G 0.67 0.00
37_K 44_M 0.67 0.00
32_P 63_T 0.67 0.00
9_K 55_K 0.66 0.00
39_M 52_Y 0.66 0.00
17_D 69_H 0.66 0.00
21_S 58_V 0.66 0.00
39_M 17_E 0.65 0.00
18_A 85_K 0.65 0.00
25_L 14_H 0.65 0.00
42_P 37_R 0.64 0.00
10_K 59_P 0.64 0.00
13_K 80_Y 0.64 0.00
32_P 45_V 0.63 0.00
11_T 32_K 0.63 0.00
15_R 29_R 0.63 0.00
47_P 55_K 0.62 0.00
14_A 62_I 0.61 0.00
20_R 59_P 0.61 0.00
40_K 22_L 0.60 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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