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OPENSEQ.org

THID - THIE
UniProt: P76422 - P30137
Length: 477
Sequences: 711
Seq/Len: 1.55
I_Prob: 0.00

THID - Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
Paralog alert: 0.62 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PDXK PDXY THID
THIE - Thiamine-phosphate synthase
Paralog alert: 0.31 [within 20: 0.06] - ratio of genomes with paralogs
Cluster includes: THIE
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
175_M 74_L 0.96 0.00
219_L 183_I 0.90 0.00
220_A 99_R 0.85 0.00
104_L 126_I 0.79 0.00
37_V 121_A 0.75 0.00
125_L 160_P 0.74 0.00
215_L 40_I 0.74 0.00
237_K 127_A 0.74 0.00
216_S 111_D 0.74 0.00
232_T 180_V 0.74 0.00
243_A 96_N 0.73 0.00
55_I 90_L 0.72 0.00
40_A 120_A 0.72 0.00
167_A 178_T 0.71 0.00
73_I 175_V 0.71 0.00
133_V 81_Y 0.70 0.00
141_P 34_R 0.70 0.00
85_D 116_D 0.69 0.00
186_P 79_Q 0.69 0.00
35_C 99_R 0.69 0.00
90_V 195_W 0.68 0.00
208_T 134_T 0.68 0.00
106_T 66_L 0.68 0.00
127_S 50_A 0.68 0.00
109_L 111_D 0.68 0.00
101_N 109_T 0.67 0.00
150_P 57_A 0.67 0.00
87_V 29_L 0.66 0.00
136_I 168_S 0.66 0.00
162_G 117_V 0.65 0.00
232_T 85_L 0.65 0.00
160_E 77_K 0.65 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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