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OPENSEQ.org

HIGA - HIGB
UniProt: P67701 - P64578
Length: 242
Sequences: 197
Seq/Len: 0.92
I_Prob: 0.01

HIGA - Antitoxin HigA
Paralog alert: 0.29 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HIGA
HIGB - mRNA interferase HigB
Paralog alert: 0.16 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HIGB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
31_T 7_K 1.48 0.01
87_L 29_T 1.43 0.01
50_L 83_R 1.30 0.01
74_A 24_V 1.28 0.01
28_E 39_E 1.24 0.01
59_A 82_I 1.21 0.01
133_P 5_T 1.17 0.00
134_A 18_Q 1.16 0.00
89_D 82_I 1.14 0.00
26_N 5_T 1.12 0.00
40_L 81_Y 1.12 0.00
82_A 21_T 1.10 0.00
58_T 32_K 1.08 0.00
113_G 58_Y 1.04 0.00
136_F 86_M 1.02 0.00
76_A 43_A 1.01 0.00
63_S 4_I 1.01 0.00
110_V 39_E 0.99 0.00
50_L 75_F 0.99 0.00
127_T 31_A 0.98 0.00
126_A 49_D 0.98 0.00
38_D 83_R 0.98 0.00
43_N 2_H 0.97 0.00
50_L 61_N 0.97 0.00
117_L 58_Y 0.97 0.00
38_D 74_F 0.96 0.00
129_F 61_N 0.96 0.00
89_D 46_P 0.96 0.00
57_I 66_E 0.96 0.00
55_A 2_H 0.96 0.00
89_D 45_F 0.94 0.00
36_L 67_L 0.93 0.00
62_E 34_Y 0.93 0.00
73_M 89_K 0.93 0.00
27_E 32_K 0.93 0.00
94_T 36_K 0.93 0.00
83_V 3_L 0.92 0.00
25_Q 72_M 0.92 0.00
31_T 82_I 0.92 0.00
117_L 25_A 0.91 0.00
78_P 85_V 0.91 0.00
74_A 32_K 0.91 0.00
53_V 40_S 0.90 0.00
74_A 10_K 0.89 0.00
86_T 48_L 0.89 0.00
89_D 70_V 0.89 0.00
16_A 95_T 0.89 0.00
60_W 17_P 0.89 0.00
90_Q 29_T 0.88 0.00
57_I 34_Y 0.87 0.00
41_L 2_H 0.87 0.00
87_L 45_F 0.86 0.00
93_L 37_K 0.86 0.00
130_G 39_E 0.86 0.00
46_E 73_V 0.85 0.00
74_A 13_A 0.85 0.00
56_K 26_L 0.85 0.00
86_T 29_T 0.85 0.00
51_D 82_I 0.84 0.00
136_F 84_E 0.84 0.00
136_F 58_Y 0.84 0.00
74_A 79_K 0.84 0.00
53_V 78_Q 0.84 0.00
34_L 30_I 0.84 0.00
27_E 70_V 0.83 0.00
27_E 41_L 0.83 0.00
101_I 51_F 0.83 0.00
94_T 31_A 0.83 0.00
136_F 57_H 0.83 0.00
61_E 87_T 0.83 0.00
92_G 32_K 0.83 0.00
117_L 38_P 0.82 0.00
84_I 62_V 0.82 0.00
129_F 2_H 0.82 0.00
78_P 61_N 0.81 0.00
88_M 47_S 0.81 0.00
28_E 34_Y 0.80 0.00
120_E 15_K 0.79 0.00
97_D 59_V 0.79 0.00
76_A 31_A 0.79 0.00
58_T 81_Y 0.79 0.00
27_E 73_V 0.79 0.00
105_S 74_F 0.79 0.00
47_N 3_L 0.79 0.00
39_H 3_L 0.79 0.00
42_L 20_K 0.79 0.00
114_K 70_V 0.78 0.00
87_L 86_M 0.78 0.00
37_V 46_P 0.78 0.00
119_L 42_K 0.77 0.00
90_Q 44_V 0.77 0.00
86_T 12_A 0.77 0.00
98_L 64_G 0.77 0.00
33_A 85_V 0.77 0.00
101_I 52_K 0.77 0.00
49_L 17_P 0.77 0.00
104_K 85_V 0.76 0.00
127_T 27_G 0.76 0.00
137_I 65_N 0.76 0.00
86_T 3_L 0.76 0.00
135_L 70_V 0.76 0.00
41_L 24_V 0.76 0.00
110_V 85_V 0.76 0.00
64_A 60_F 0.75 0.00
119_L 11_D 0.75 0.00
131_I 86_M 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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