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OPENSEQ.org

HIS5 - PHYDA
UniProt: P60595 - Q46806
Length: 657
Sequences: 737
Seq/Len: 1.20
I_Prob: 0.00

HIS5 - Imidazole glycerol phosphate synthase subunit HisH
Paralog alert: 0.89 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: HIS5 PABA
PHYDA - D-phenylhydantoinase
Paralog alert: 0.78 [within 20: 0.20] - ratio of genomes with paralogs
Cluster includes: ALLB CODA GUAD IADA NAGA PHNM PHYDA SSNA YAHJ
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
177_F 224_I 1.14 0.00
177_F 79_T 1.01 0.00
145_Y 299_W 0.99 0.00
68_A 384_A 0.95 0.00
194_L 429_L 0.94 0.00
24_G 42_E 0.93 0.00
83_L 280_G 0.87 0.00
67_K 15_G 0.86 0.00
6_L 44_I 0.84 0.00
83_L 10_V 0.83 0.00
166_A 237_I 0.81 0.00
43_F 21_L 0.80 0.00
106_M 170_R 0.80 0.00
145_Y 303_S 0.79 0.00
2_N 247_D 0.79 0.00
82_L 25_S 0.78 0.00
43_F 211_R 0.78 0.00
177_F 70_R 0.77 0.00
180_E 183_P 0.76 0.00
66_I 361_R 0.76 0.00
2_N 367_S 0.76 0.00
154_I 376_L 0.75 0.00
188_K 77_T 0.75 0.00
20_I 176_G 0.75 0.00
37_L 6_K 0.74 0.00
5_I 89_T 0.74 0.00
133_I 248_Y 0.73 0.00
84_G 263_T 0.72 0.00
4_V 30_Q 0.72 0.00
102_D 374_F 0.72 0.00
133_I 23_I 0.72 0.00
73_V 368_A 0.71 0.00
20_I 250_R 0.71 0.00
129_L 49_C 0.71 0.00
101_E 390_D 0.70 0.00
83_L 36_S 0.70 0.00
167_V 3_V 0.70 0.00
24_G 310_V 0.70 0.00
27_P 79_T 0.70 0.00
32_D 354_T 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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