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OPENSEQ.org

L27 - S19
UniProt: P60493 - Q5SHP2
Length: 178
Sequences: 1100
Seq/Len: 6.32
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2d0 3v2eS 3v2f0Contact Map
2j002j00S 2j010 2j02S 2j030Contact Map
4juw4juwS 4jux0Contact Map
4kix4kixW 4kiyS 4kizW 4kj0S 4kj1W 4kj2S 4kj3W 4kj4SContact Map
4kj54kj5W 4kj6S 4kj7W 4kj8S 4kj9W 4kjaS 4kjbW 4kjcSContact Map
3uyd3uydV 3uye3 3uyfV 3uyg3Contact Map
4gd13r8sW 3r8tW 4gd1S 4gd2SContact Map
3knh3knhS 3kni0 3knjS 3knk0Contact Map
3ohc3ohcS 3ohdS 3ohj0 3ohk0Contact Map
3ohy3ohyS 3ohz0 3oi0S 3oi10Contact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
6_G 81_R 0.95 0.01
46_K 52_Y 0.87 0.01
10_T 64_E 0.87 0.01
7_L 47_H 0.83 0.01
11_R 63_T 0.77 0.01
72_R 63_T 0.76 0.01
11_R 66_M 0.76 0.01
7_L 85_K 0.75 0.01
38_V 44_M 0.75 0.01
76_G 31_I 0.72 0.01
45_F 41_V 0.72 0.01
51_V 18_K 0.72 0.01
10_T 12_D 0.70 0.01
74_R 39_T 0.69 0.01
43_T 67_V 0.67 0.01
45_F 29_R 0.67 0.01
10_T 85_K 0.67 0.01
63_V 37_R 0.66 0.01
32_R 87_A 0.66 0.01
57_F 87_A 0.66 0.01
33_A 84_G 0.65 0.01
7_L 12_D 0.64 0.01
78_Y 39_T 0.63 0.01
32_R 62_I 0.63 0.01
27_E 41_V 0.63 0.01
5_K 34_W 0.62 0.01
84_L 26_G 0.61 0.01
3_H 46_G 0.61 0.01
8_G 85_K 0.60 0.01
75_L 27_E 0.59 0.01
25_R 53_N 0.59 0.01
13_G 69_H 0.59 0.01
14_R 1_M 0.58 0.01
7_L 86_E 0.58 0.01
6_G 65_N 0.57 0.01
52_G 70_K 0.56 0.00
21_L 57_H 0.56 0.00
49_K 43_E 0.56 0.00
73_G 44_M 0.56 0.00
18_A 57_H 0.56 0.00
45_F 57_H 0.56 0.00
25_R 2_P 0.55 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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