May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
L21 - S19
UniProt: P60492 - Q5SHP2
Length: 194
Sequences: 1137
Seq/Len: 5.95
I_Prob: 0.07
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2dV 3v2eS 3v2fVContact Map
2j002j00S 2j01V 2j02S 2j03VContact Map
4juw4juwS 4juxVContact Map
4kix4kixR 4kiyS 4kizR 4kj0S 4kj1R 4kj2S 4kj3R 4kj4SContact Map
4kj54kj5R 4kj6S 4kj7R 4kj8S 4kj9R 4kjaS 4kjbR 4kjcSContact Map
3uyd3uydV 3uye2 3uyfV 3uyg2Contact Map
4gd13r8sR 3r8tR 4gd1S 4gd2SContact Map
3ohc3ohcS 3ohdS 3ohjV 3ohkVContact Map
3knh3knhS 3kniV 3knjS 3knkVContact Map
3ohy3ohyS 3ohzV 3oi0S 3oi1VContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
76_K 30_L 1.06 0.07
75_F 57_H 1.01 0.06
21_R 44_M 0.89 0.04
67_G 80_Y 0.80 0.03
63_G 27_E 0.76 0.02
78_K 23_N 0.73 0.02
20_L 31_I 0.72 0.02
79_V 85_K 0.72 0.02
26_D 62_I 0.69 0.02
53_E 24_A 0.68 0.02
7_T 66_M 0.68 0.02
27_A 37_R 0.67 0.02
66_R 49_I 0.67 0.02
51_V 44_M 0.67 0.02
30_G 45_V 0.65 0.02
35_L 65_N 0.64 0.01
23_E 63_T 0.64 0.01
77_A 65_N 0.64 0.01
24_K 45_V 0.62 0.01
95_L 40_I 0.61 0.01
35_L 86_E 0.61 0.01
13_R 89_A 0.60 0.01
53_E 40_I 0.60 0.01
83_R 11_V 0.59 0.01
73_S 39_T 0.58 0.01
77_A 37_R 0.57 0.01
94_L 26_G 0.56 0.01
12_Y 29_R 0.56 0.01
71_L 43_E 0.56 0.01
67_G 76_P 0.56 0.01
95_L 12_D 0.56 0.01
97_K 2_P 0.55 0.01
83_R 52_Y 0.55 0.01
2_F 61_Y 0.55 0.01
82_R 76_P 0.55 0.01
78_K 87_A 0.55 0.01
5_V 58_V 0.54 0.01
67_G 46_G 0.54 0.01
5_V 30_L 0.54 0.01
12_Y 5_L 0.54 0.01
63_G 44_M 0.54 0.01
54_G 44_M 0.53 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.528 seconds.