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OPENSEQ.org

L16 - S19
UniProt: P60489 - Q5SHP2
Length: 234
Sequences: 1110
Seq/Len: 4.87
I_Prob: 0.02
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2dQ 3v2eS 3v2fQContact Map
2j002j00S 2j01Q 2j02S 2j03QContact Map
4juw4juwS 4juxQContact Map
4kix4kixM 4kiyS 4kizM 4kj0S 4kj1M 4kj2S 4kj3M 4kj4SContact Map
4kj54kj5M 4kj6S 4kj7M 4kj8S 4kj9M 4kjaS 4kjbM 4kjcSContact Map
3knh3knhS 3kniQ 3knjS 3knkQContact Map
3ohc3ohcS 3ohdS 3ohjQ 3ohkQContact Map
3uz63uz6V 3uz7V 3uz8P 3uz9PContact Map
3oge3ogeS 3ogyS 3oh5Q 3oh7QContact Map
3uyd3uydV 3uyeP 3uyfV 3uygPContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
67_R 53_N 1.00 0.02
7_M 56_Q 0.92 0.02
3_M 12_D 0.87 0.02
81_V 52_Y 0.86 0.02
41_W 2_P 0.83 0.01
85_K 24_A 0.81 0.01
119_R 30_L 0.80 0.01
7_M 53_N 0.78 0.01
45_Q 80_Y 0.77 0.01
14_R 22_L 0.77 0.01
85_K 80_Y 0.76 0.01
130_K 27_E 0.76 0.01
42_I 75_A 0.75 0.01
137_Y 44_M 0.75 0.01
23_G 37_R 0.73 0.01
136_A 26_G 0.72 0.01
85_K 57_H 0.71 0.01
101_R 52_Y 0.71 0.01
13_Q 20_L 0.71 0.01
62_G 68_G 0.71 0.01
81_V 86_E 0.70 0.01
65_F 59_P 0.70 0.01
34_L 29_R 0.70 0.01
127_I 45_V 0.69 0.01
17_L 49_I 0.69 0.01
67_R 65_N 0.68 0.01
53_A 51_V 0.67 0.01
110_T 62_I 0.67 0.01
77_K 65_N 0.67 0.01
125_L 32_K 0.66 0.01
18_K 62_I 0.66 0.01
106_V 37_R 0.66 0.01
40_A 75_A 0.66 0.01
14_R 57_H 0.65 0.01
26_Y 62_I 0.65 0.01
72_K 61_Y 0.65 0.01
101_R 32_K 0.65 0.01
72_K 49_I 0.64 0.01
131_I 11_V 0.64 0.01
18_K 24_A 0.64 0.01
133_R 45_V 0.63 0.01
52_V 57_H 0.63 0.01
63_K 44_M 0.63 0.01
134_R 2_P 0.63 0.01
129_T 18_K 0.62 0.01
137_Y 25_K 0.62 0.01
58_F 44_M 0.62 0.01
9_Y 67_V 0.62 0.01
10_R 69_H 0.62 0.01
76_K 65_N 0.62 0.01
90_V 80_Y 0.61 0.01
27_V 57_H 0.61 0.01
20_A 88_K 0.61 0.01
96_V 61_Y 0.61 0.01
61_G 29_R 0.61 0.01
136_A 49_I 0.60 0.01
57_H 79_T 0.60 0.01
130_K 28_K 0.60 0.01
133_R 16_L 0.60 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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