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OPENSEQ.org
MTOX - THIS
UniProt: P40874 - O32583
Length: 438
Sequences: 380
Seq/Len: 0.88
I_Prob: 0.00
MTOX - N-methyl-L-tryptophan oxidase
Paralog alert: 0.81 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: DADA LHGO MTOX PUUB 		THIS - Sulfur carrier protein ThiS
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: THIS
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1y56B:A:AContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
164_C 56_Q 1.44 0.00
12_S 55_D 1.32 0.00
217_R 38_Q 1.31 0.00
289_F 1_M 1.23 0.00
117_L 55_D 1.21 0.00
226_D 22_L 1.21 0.00
308_C 60_F 1.21 0.00
330_L 13_A 1.17 0.00
364_T 11_Q 1.13 0.00
43_H 63_I 1.12 0.00
28_V 39_Q 1.11 0.00
27_N 13_A 1.08 0.00
66_R 39_Q 1.07 0.00
7_I 48_Q 1.07 0.00
196_A 25_L 1.06 0.00
289_F 64_A 1.00 0.00
92_L 36_I 0.99 0.00
253_A 64_A 0.98 0.00
260_I 20_E 0.98 0.00
289_F 35_A 0.97 0.00
302_C 43_R 0.95 0.00
149_E 40_I 0.94 0.00
121_G 51_V 0.94 0.00
217_R 18_V 0.93 0.00
12_S 19_H 0.93 0.00
317_D 38_Q 0.93 0.00
316_E 58_L 0.93 0.00
223_Y 64_A 0.92 0.00
89_V 60_F 0.92 0.00
148_S 63_I 0.92 0.00
346_L 58_L 0.92 0.00
294_N 25_L 0.91 0.00
301_C 54_G 0.91 0.00
138_L 41_V 0.91 0.00
276_V 7_D 0.91 0.00
203_W 25_L 0.91 0.00
88_G 55_D 0.91 0.00
291_F 37_N 0.91 0.00
250_G 41_V 0.91 0.00
60_Y 49_H 0.90 0.00
88_G 37_N 0.90 0.00
28_V 57_I 0.89 0.00
307_A 49_H 0.89 0.00
124_A 11_Q 0.89 0.00
108_E 57_I 0.88 0.00
237_A 63_I 0.88 0.00
291_F 62_V 0.87 0.00
292_L 64_A 0.87 0.00
84_F 22_L 0.87 0.00
7_I 18_V 0.87 0.00
302_C 60_F 0.87 0.00
197_I 21_L 0.86 0.00
67_A 56_Q 0.86 0.00
214_Q 33_A 0.86 0.00
320_I 49_H 0.86 0.00
164_C 3_I 0.86 0.00
81_D 1_M 0.85 0.00
7_I 37_N 0.85 0.00
43_H 64_A 0.85 0.00
6_I 29_Q 0.85 0.00
250_G 19_H 0.85 0.00
256_D 7_D 0.85 0.00
213_V 11_Q 0.84 0.00
354_A 59_L 0.84 0.00
46_D 35_A 0.84 0.00
5_L 40_I 0.84 0.00
291_F 42_P 0.84 0.00
119_A 19_H 0.83 0.00
197_I 17_T 0.83 0.00
125_R 18_V 0.83 0.00
258_L 59_L 0.83 0.00
214_Q 64_A 0.82 0.00
135_Y 60_F 0.82 0.00
72_D 39_Q 0.82 0.00
220_F 1_M 0.82 0.00
7_I 44_E 0.82 0.00
124_A 9_A 0.82 0.00
316_E 25_L 0.81 0.00
93_G 64_A 0.81 0.00
39_Q 5_F 0.81 0.00
23_R 25_L 0.81 0.00
134_N 32_A 0.81 0.00
24_A 61_Q 0.81 0.00
344_S 58_L 0.81 0.00
290_P 42_P 0.80 0.00
7_I 55_D 0.80 0.00
190_E 50_I 0.80 0.00
31_T 22_L 0.80 0.00
34_H 53_D 0.79 0.00
137_G 13_A 0.79 0.00
86_R 44_E 0.79 0.00
357_K 59_L 0.79 0.00
315_D 57_I 0.79 0.00
164_C 11_Q 0.79 0.00
30_M 1_M 0.79 0.00
65_L 53_D 0.79 0.00
335_L 55_D 0.78 0.00
198_V 12_C 0.78 0.00
104_A 58_L 0.78 0.00
342_F 32_A 0.78 0.00
247_Q 60_F 0.78 0.00
161_E 43_R 0.78 0.00
193_A 29_Q 0.77 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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