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OPENSEQ.org
L33 - S19
UniProt: P35871 - Q5SHP2
Length: 147
Sequences: 909
Seq/Len: 6.40
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3v2c3v2cS 3v2d6 3v2eS 3v2f6Contact Map
2j002j00S 2j016 2j02S 2j036Contact Map
4juw4juwS 4jux6Contact Map
4kix4kix1 4kiyS 4kiz1 4kj0S 4kj11 4kj2S 4kj31 4kj4SContact Map
4kj54kj51 4kj6S 4kj71 4kj8S 4kj91 4kjaS 4kjb1 4kjcSContact Map
3uyd3uydV 3uye6 3uyfV 3uyg6Contact Map
4gd13r8s1 3r8t1 4gd1S 4gd2SContact Map
3knh3knhS 3kni6 3knjS 3knk6Contact Map
3ohc3ohcS 3ohdS 3ohj6 3ohk6Contact Map
3f1e3f1eS 3f1f6 3f1gS 3f1h6Contact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
50_R 78_R 0.93 0.01
50_R 8_G 0.92 0.01
8_K 57_H 0.85 0.01
52_V 64_E 0.77 0.01
44_R 78_R 0.76 0.01
46_H 22_L 0.76 0.01
36_L 76_P 0.73 0.01
18_R 39_T 0.73 0.01
12_E 56_Q 0.71 0.01
33_K 53_N 0.67 0.01
18_R 12_D 0.64 0.01
27_K 29_R 0.64 0.01
14_T 32_K 0.63 0.01
17_K 39_T 0.63 0.01
49_H 76_P 0.63 0.01
39_Y 58_V 0.62 0.01
49_H 51_V 0.61 0.01
29_N 44_M 0.60 0.00
18_R 37_R 0.59 0.00
34_L 20_L 0.58 0.00
6_R 46_G 0.58 0.00
46_H 29_R 0.58 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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