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THIE - THIF
UniProt: P30137 - P30138
Length: 462
Sequences: 386
Seq/Len: 0.86
I_Prob: 0.00

THIE - Thiamine-phosphate synthase
Paralog alert: 0.31 [within 20: 0.06] - ratio of genomes with paralogs
Cluster includes: THIE
THIF - Sulfur carrier protein ThiS adenylyltransferase
Paralog alert: 0.69 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MOEB THIF YGDL
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
79_Q 115_A 1.33 0.00
143_P 194_V 1.14 0.00
150_A 25_K 1.13 0.00
175_V 192_P 1.10 0.00
38_L 53_G 1.08 0.00
66_L 122_V 1.07 0.00
34_R 66_S 1.06 0.00
184_A 91_L 1.06 0.00
38_L 26_L 1.06 0.00
162_V 122_V 1.06 0.00
162_V 208_L 1.05 0.00
187_S 237_A 1.02 0.00
38_L 170_Y 1.00 0.00
159_Y 107_L 1.00 0.00
187_S 72_I 0.98 0.00
186_V 146_L 0.98 0.00
193_A 122_V 0.94 0.00
167_I 40_G 0.94 0.00
99_R 149_A 0.93 0.00
112_D 121_V 0.92 0.00
172_A 123_L 0.92 0.00
15_L 69_Q 0.92 0.00
47_E 110_E 0.91 0.00
71_Y 156_G 0.91 0.00
47_E 30_Q 0.91 0.00
18_V 125_C 0.90 0.00
27_R 64_H 0.90 0.00
52_V 98_I 0.89 0.00
112_D 115_A 0.89 0.00
150_A 74_F 0.88 0.00
131_V 88_Q 0.88 0.00
43_R 189_V 0.87 0.00
99_R 197_M 0.86 0.00
97_A 33_I 0.86 0.00
186_V 148_T 0.86 0.00
21_S 74_F 0.86 0.00
59_G 6_F 0.86 0.00
154_E 208_L 0.86 0.00
61_R 74_F 0.86 0.00
33_V 95_N 0.85 0.00
23_Q 98_I 0.85 0.00
183_I 161_L 0.84 0.00
146_L 176_D 0.82 0.00
204_E 93_Q 0.82 0.00
16_Y 201_Q 0.82 0.00
105_L 209_L 0.81 0.00
36_L 29_S 0.81 0.00
106_G 149_A 0.81 0.00
69_N 64_H 0.81 0.00
115_I 116_V 0.81 0.00
34_R 19_A 0.81 0.00
89_D 175_P 0.81 0.00
183_I 208_L 0.81 0.00
187_S 152_V 0.80 0.00
202_L 132_R 0.79 0.00
25_I 146_L 0.78 0.00
171_R 135_I 0.78 0.00
131_V 20_L 0.78 0.00
33_V 209_L 0.78 0.00
82_G 120_D 0.78 0.00
189_I 153_G 0.77 0.00
23_Q 69_Q 0.77 0.00
108_S 240_C 0.77 0.00
118_A 201_Q 0.77 0.00
29_L 224_G 0.77 0.00
28_L 100_L 0.77 0.00
130_H 194_V 0.77 0.00
26_E 28_D 0.77 0.00
48_V 188_G 0.77 0.00
56_I 55_L 0.77 0.00
169_L 30_Q 0.76 0.00
77_K 98_I 0.76 0.00
160_P 201_Q 0.76 0.00
22_V 98_I 0.76 0.00
194_D 63_V 0.75 0.00
183_I 5_D 0.75 0.00
150_A 108_T 0.75 0.00
155_R 33_I 0.75 0.00
167_I 233_A 0.75 0.00
40_I 191_G 0.75 0.00
184_A 123_L 0.75 0.00
163_A 136_N 0.74 0.00
180_V 34_I 0.74 0.00
200_A 88_Q 0.74 0.00
182_S 149_A 0.74 0.00
100_A 149_A 0.74 0.00
191_Q 186_T 0.74 0.00
69_N 107_L 0.74 0.00
14_G 125_C 0.74 0.00
186_V 194_V 0.73 0.00
196_R 88_Q 0.73 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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