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OPENSEQ.org

ARGE - METB
UniProt: P23908 - P00935
Length: 769
Sequences: 507
Seq/Len: 0.67
I_Prob: 0.00

ARGE - Acetylornithine deacetylase
Paralog alert: 0.89 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: ABGA ABGB ALLC ARGE DAPE PEPT YGEY
METB - Cystathionine gamma-synthase
Paralog alert: 0.82 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: METB METC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1q7lAC:BDContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
241_L 117_Y 0.93 0.00
64_M 140_L 0.92 0.00
76_L 178_S 0.91 0.00
187_I 27_I 0.85 0.00
163_D 31_S 0.85 0.00
10_E 78_S 0.83 0.00
189_I 200_L 0.83 0.00
215_H 117_Y 0.83 0.00
322_G 183_N 0.79 0.00
206_I 104_S 0.79 0.00
16_I 33_Y 0.77 0.00
166_I 362_I 0.76 0.00
75_L 126_D 0.73 0.00
319_K 165_E 0.73 0.00
45_D 187_L 0.72 0.00
95_P 362_I 0.71 0.00
136_L 10_V 0.70 0.00
187_I 285_G 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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