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OPENSEQ.org

GSA - HEM3
UniProt: P23893 - P06983
Length: 739
Sequences: 469
Seq/Len: 0.64
I_Prob: 0.00

GSA - Glutamate-1-semialdehyde 2,1-aminomutase
Paralog alert: 0.89 [within 20: 0.12] - ratio of genomes with paralogs
Cluster includes: ARGD ASTC BIOA GABT GSA PAT PUUE
HEM3 - Porphobilinogen deaminase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM3
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
179_C 166_A 1.19 0.00
36_I 148_L 1.14 0.00
353_G 241_G 1.11 0.00
208_G 78_A 1.08 0.00
134_K 261_A 1.03 0.00
379_F 8_I 1.02 0.00
5_E 20_A 1.02 0.00
83_L 197_G 0.98 0.00
382_F 201_V 0.97 0.00
177_L 77_I 0.97 0.00
372_M 18_W 0.96 0.00
403_M 9_A 0.95 0.00
68_H 71_L 0.94 0.00
207_A 56_V 0.94 0.00
191_F 299_A 0.93 0.00
135_I 128_S 0.93 0.00
287_A 166_A 0.91 0.00
98_L 166_A 0.91 0.00
89_T 224_T 0.91 0.00
219_F 102_E 0.90 0.00
379_F 200_A 0.90 0.00
39_A 214_E 0.90 0.00
185_A 241_G 0.89 0.00
27_T 77_I 0.89 0.00
43_Y 98_I 0.89 0.00
214_P 183_I 0.88 0.00
306_A 162_G 0.88 0.00
223_L 187_L 0.88 0.00
83_L 238_L 0.87 0.00
158_L 99_C 0.87 0.00
62_M 109_V 0.87 0.00
139_E 152_V 0.87 0.00
354_M 78_A 0.87 0.00
303_I 8_I 0.87 0.00
119_T 247_G 0.86 0.00
9_S 207_L 0.86 0.00
38_K 219_L 0.86 0.00
212_C 148_L 0.85 0.00
337_E 181_S 0.85 0.00
53_I 144_I 0.85 0.00
281_D 98_I 0.84 0.00
32_T 125_V 0.84 0.00
212_C 55_K 0.84 0.00
300_G 135_Q 0.84 0.00
407_H 197_G 0.84 0.00
222_G 123_S 0.83 0.00
267_I 141_P 0.83 0.00
420_R 104_P 0.83 0.00
188_R 125_V 0.83 0.00
106_M 205_C 0.82 0.00
97_Q 152_V 0.82 0.00
407_H 247_G 0.82 0.00
200_C 137_A 0.82 0.00
151_V 152_V 0.81 0.00
113_N 88_E 0.81 0.00
371_V 79_V 0.81 0.00
149_L 204_E 0.81 0.00
93_V 93_L 0.81 0.00
258_P 165_D 0.80 0.00
132_R 249_Y 0.80 0.00
201_I 187_L 0.80 0.00
97_Q 222_H 0.80 0.00
74_A 162_G 0.80 0.00
409_M 136_L 0.80 0.00
240_M 243_Q 0.79 0.00
81_R 168_I 0.79 0.00
372_M 128_S 0.79 0.00
157_A 201_V 0.78 0.00
293_Y 9_A 0.78 0.00
353_G 17_L 0.78 0.00
333_E 214_E 0.78 0.00
99_V 71_L 0.78 0.00
59_W 67_E 0.77 0.00
240_M 219_L 0.77 0.00
191_F 246_I 0.76 0.00
224_R 78_A 0.76 0.00
164_N 249_Y 0.76 0.00
158_L 82_M 0.76 0.00
169_P 56_V 0.76 0.00
161_G 215_L 0.76 0.00
4_S 75_A 0.76 0.00
177_L 95_L 0.75 0.00
111_M 160_D 0.75 0.00
42_A 104_P 0.75 0.00
81_R 124_I 0.75 0.00
263_L 179_L 0.75 0.00
161_G 59_K 0.75 0.00
224_R 156_L 0.75 0.00
185_A 141_P 0.75 0.00
181_Y 204_E 0.75 0.00
321_H 299_A 0.75 0.00
354_M 123_S 0.75 0.00
419_A 110_S 0.74 0.00
16_P 9_A 0.74 0.00
9_S 125_V 0.74 0.00
408_S 144_I 0.74 0.00
62_M 8_I 0.74 0.00
303_I 137_A 0.74 0.00
168_V 152_V 0.74 0.00
300_G 16_A 0.74 0.00
95_M 110_S 0.74 0.00
412_I 90_P 0.74 0.00
262_C 44_R 0.74 0.00
165_S 156_L 0.73 0.00
119_T 119_L 0.73 0.00
338_A 85_V 0.73 0.00
100_T 85_V 0.73 0.00
377_E 8_I 0.73 0.00
95_M 190_E 0.73 0.00
310_A 77_I 0.73 0.00
106_M 7_R 0.73 0.00
408_S 68_V 0.73 0.00
200_C 307_Y 0.73 0.00
145_H 204_E 0.73 0.00
255_G 257_I 0.72 0.00
287_A 259_L 0.72 0.00
232_A 154_T 0.72 0.00
129_F 137_A 0.72 0.00
76_I 247_G 0.72 0.00
299_S 16_A 0.71 0.00
240_M 42_V 0.71 0.00
229_E 73_N 0.71 0.00
407_H 53_L 0.71 0.00
223_L 47_V 0.71 0.00
255_G 125_V 0.71 0.00
160_L 20_A 0.71 0.00
424_A 109_V 0.71 0.00
227_C 49_L 0.71 0.00
380_K 247_G 0.71 0.00
388_D 217_A 0.71 0.00
164_N 12_Q 0.70 0.00
102_L 58_G 0.70 0.00
230_F 72_E 0.70 0.00
141_C 278_G 0.70 0.00
97_Q 38_L 0.70 0.00
364_S 247_G 0.70 0.00
407_H 8_I 0.70 0.00
268_G 53_L 0.70 0.00
263_L 27_L 0.70 0.00
319_G 152_V 0.69 0.00
197_E 70_L 0.69 0.00
393_L 12_Q 0.69 0.00
298_L 204_E 0.69 0.00
106_M 225_A 0.69 0.00
87_A 64_K 0.69 0.00
285_A 251_E 0.69 0.00
354_M 202_G 0.69 0.00
418_A 209_D 0.69 0.00
408_S 77_I 0.69 0.00
352_G 76_D 0.69 0.00
70_A 282_D 0.69 0.00
200_C 27_L 0.69 0.00
320_V 187_L 0.69 0.00
408_S 179_L 0.69 0.00
271_M 156_L 0.69 0.00
368_Y 93_L 0.69 0.00
310_A 187_L 0.69 0.00
101_E 92_G 0.68 0.00
183_D 25_D 0.68 0.00
233_L 273_R 0.68 0.00
111_M 18_W 0.68 0.00
368_Y 183_I 0.68 0.00
274_G 82_M 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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