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OPENSEQ.org

FRE - ULAD
UniProt: P0AEN1 - P39304
Length: 449
Sequences: 247
Seq/Len: 0.60
I_Prob: 0.00

FRE - NAD(P)H-flavin reductase
Paralog alert: 0.73 [within 20: 0.08] - ratio of genomes with paralogs
Cluster includes: FENR FRE
ULAD - 3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Paralog alert: 0.49 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PYRF SGBH ULAD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1ep3B:AContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
63_L 39_C 1.41 0.00
51_M 190_A 1.22 0.00
116_S 204_A 1.16 0.00
37_L 6_L 1.14 0.00
104_R 210_S 1.12 0.00
116_S 188_F 1.06 0.00
144_Q 209_R 1.03 0.00
137_Y 59_V 1.00 0.00
38_M 91_D 1.00 0.00
148_D 153_I 0.99 0.00
22_R 198_A 0.99 0.00
156_S 186_H 0.97 0.00
116_S 121_Q 0.97 0.00
18_V 208_K 0.96 0.00
23_I 128_A 0.96 0.00
198_I 163_G 0.94 0.00
212_D 97_G 0.94 0.00
83_K 162_M 0.94 0.00
33_A 19_Y 0.93 0.00
46_K 90_A 0.93 0.00
39_V 59_V 0.93 0.00
102_E 93_N 0.92 0.00
63_L 188_F 0.92 0.00
181_T 172_L 0.92 0.00
47_R 85_T 0.91 0.00
45_D 94_T 0.91 0.00
46_K 94_T 0.90 0.00
199_Y 88_C 0.89 0.00
61_I 150_E 0.89 0.00
17_T 6_L 0.88 0.00
38_M 36_T 0.88 0.00
181_T 197_A 0.88 0.00
126_L 50_L 0.88 0.00
121_I 50_L 0.87 0.00
51_M 172_L 0.87 0.00
205_E 119_W 0.86 0.00
184_T 77_F 0.86 0.00
146_L 109_V 0.86 0.00
85_H 210_S 0.86 0.00
122_L 39_C 0.85 0.00
39_V 50_L 0.85 0.00
17_T 199_S 0.85 0.00
207_A 34_V 0.85 0.00
96_A 37_I 0.84 0.00
108_L 32_I 0.84 0.00
207_A 57_K 0.84 0.00
57_E 179_L 0.83 0.00
52_A 186_H 0.83 0.00
152_L 195_R 0.83 0.00
121_I 195_R 0.83 0.00
52_A 119_W 0.83 0.00
8_V 53_L 0.83 0.00
39_V 5_M 0.82 0.00
116_S 150_E 0.82 0.00
91_I 91_D 0.82 0.00
138_W 98_A 0.82 0.00
37_L 161_D 0.81 0.00
39_V 202_E 0.81 0.00
184_T 19_Y 0.81 0.00
47_R 113_L 0.81 0.00
181_T 168_V 0.81 0.00
152_L 153_I 0.81 0.00
73_Y 66_A 0.81 0.00
136_I 41_G 0.81 0.00
115_F 81_A 0.80 0.00
170_Q 59_V 0.80 0.00
197_D 193_S 0.80 0.00
92_P 91_D 0.80 0.00
93_H 34_V 0.80 0.00
109_I 99_L 0.79 0.00
140_G 121_Q 0.79 0.00
82_L 123_Q 0.79 0.00
193_L 80_N 0.79 0.00
126_L 210_S 0.79 0.00
166_P 47_V 0.78 0.00
207_A 76_C 0.78 0.00
9_T 128_A 0.78 0.00
198_I 27_E 0.78 0.00
39_V 199_S 0.78 0.00
87_I 163_G 0.78 0.00
107_I 84_V 0.78 0.00
42_D 84_V 0.78 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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