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OPENSEQ.org

CPXA - MACA
UniProt: P0AE82 - P75830
Length: 828
Sequences: 478
Seq/Len: 0.61
I_Prob: 0.00

CPXA - Sensor protein CpxA
Paralog alert: 0.73 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: ATOS BAES BASS CPXA CREC CUSS DCUS DPIB ENVZ GLRK NTRB PHOQ PHOR QSEC RSTB YEDV ZRAS
MACA - Macrolide-specific efflux protein MacA
Paralog alert: 0.76 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: AAEA ACRA ACRE EMRA EMRK MACA MDTA MDTE MDTN YBHG YDHJ YHII YIAV YIBH
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
404_Y 188_A 1.33 0.00
310_A 348_V 1.07 0.00
146_I 339_T 1.05 0.00
196_A 188_A 1.05 0.00
317_V 309_I 1.04 0.00
193_L 262_V 1.02 0.00
288_I 190_M 1.00 0.00
190_A 245_F 0.99 0.00
396_R 217_L 0.98 0.00
361_A 309_I 0.98 0.00
284_L 112_R 0.97 0.00
363_R 259_I 0.97 0.00
206_R 282_P 0.96 0.00
22_M 340_I 0.95 0.00
87_L 331_G 0.94 0.00
169_I 358_D 0.94 0.00
184_W 358_D 0.94 0.00
95_I 72_L 0.93 0.00
451_L 282_P 0.90 0.00
188_K 314_L 0.90 0.00
406_T 87_Q 0.90 0.00
53_V 314_L 0.90 0.00
409_A 246_T 0.90 0.00
435_V 217_L 0.89 0.00
449_I 298_I 0.89 0.00
193_L 173_S 0.89 0.00
347_P 350_I 0.89 0.00
393_P 340_I 0.89 0.00
332_L 319_G 0.88 0.00
307_T 298_I 0.88 0.00
257_L 72_L 0.88 0.00
355_E 214_I 0.88 0.00
378_D 92_I 0.87 0.00
232_L 242_K 0.87 0.00
437_A 358_D 0.87 0.00
382_I 357_G 0.87 0.00
169_I 307_L 0.86 0.00
397_E 296_V 0.86 0.00
332_L 339_T 0.86 0.00
246_I 314_L 0.85 0.00
392_S 130_S 0.85 0.00
200_V 231_E 0.85 0.00
218_F 243_A 0.84 0.00
422_A 360_V 0.83 0.00
310_A 287_L 0.83 0.00
427_A 115_R 0.83 0.00
179_L 362_I 0.83 0.00
343_L 60_R 0.83 0.00
11_A 258_Q 0.83 0.00
382_I 358_D 0.83 0.00
225_F 270_N 0.82 0.00
371_V 304_K 0.82 0.00
346_N 272_A 0.81 0.00
165_L 361_V 0.81 0.00
358_V 270_N 0.81 0.00
402_P 111_L 0.81 0.00
331_S 301_T 0.81 0.00
237_T 191_A 0.80 0.00
211_L 112_R 0.80 0.00
193_L 79_I 0.80 0.00
89_T 350_I 0.80 0.00
383_T 340_I 0.79 0.00
322_A 309_I 0.79 0.00
240_Q 199_T 0.79 0.00
191_R 234_V 0.79 0.00
397_E 160_I 0.79 0.00
65_L 350_I 0.78 0.00
15_L 219_D 0.78 0.00
382_I 198_T 0.78 0.00
364_Y 60_R 0.78 0.00
308_I 214_I 0.78 0.00
331_S 360_V 0.78 0.00
16_T 295_Q 0.78 0.00
382_I 210_Q 0.78 0.00
249_E 142_S 0.77 0.00
99_R 229_V 0.77 0.00
198_D 360_V 0.77 0.00
188_K 300_L 0.77 0.00
280_E 188_A 0.77 0.00
198_D 351_V 0.77 0.00
288_I 39_L 0.77 0.00
201_A 56_L 0.77 0.00
172_M 194_V 0.77 0.00
259_L 72_L 0.77 0.00
312_Q 309_I 0.77 0.00
130_G 309_I 0.77 0.00
399_I 191_A 0.77 0.00
374_A 361_V 0.77 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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