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OPENSEQ.org

HEM2 - HEM4
UniProt: P0ACB2 - P09126
Length: 570
Sequences: 453
Seq/Len: 0.81
I_Prob: 0.00

HEM2 - Delta-aminolevulinic acid dehydratase
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM2
HEM4 - Uroporphyrinogen-III synthase
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: HEM4
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
124_Y 103_I 1.23 0.00
260_R 182_V 1.11 0.00
162_I 5_V 1.02 0.00
279_I 93_L 0.98 0.00
277_A 84_Y 0.97 0.00
76_V 17_S 0.91 0.00
47_V 114_V 0.88 0.00
102_M 139_E 0.85 0.00
91_D 245_L 0.85 0.00
116_M 110_E 0.84 0.00
255_I 240_A 0.83 0.00
81_I 92_A 0.83 0.00
177_Q 117_Q 0.82 0.00
287_A 55_L 0.81 0.00
101_R 65_A 0.80 0.00
47_V 3_I 0.80 0.00
75_S 111_I 0.79 0.00
129_H 214_V 0.79 0.00
103_S 180_T 0.79 0.00
31_L 183_V 0.79 0.00
272_V 170_E 0.78 0.00
65_I 116_L 0.78 0.00
144_L 89_R 0.77 0.00
295_L 114_V 0.77 0.00
26_L 147_A 0.77 0.00
92_A 59_L 0.76 0.00
264_E 230_I 0.75 0.00
114_I 90_T 0.75 0.00
189_I 212_L 0.75 0.00
307_D 30_P 0.74 0.00
244_L 129_A 0.74 0.00
166_A 79_P 0.74 0.00
206_E 232_V 0.74 0.00
237_E 212_L 0.74 0.00
299_G 220_K 0.74 0.00
100_A 110_E 0.74 0.00
32_V 139_E 0.74 0.00
143_T 35_S 0.74 0.00
22_E 237_D 0.73 0.00
293_V 234_D 0.73 0.00
166_A 6_T 0.73 0.00
73_I 84_Y 0.73 0.00
133_L 233_A 0.72 0.00
119_T 173_R 0.72 0.00
320_K 240_A 0.72 0.00
172_V 17_S 0.72 0.00
311_S 223_R 0.72 0.00
75_S 241_L 0.72 0.00
223_P 96_H 0.72 0.00
156_A 129_A 0.72 0.00
122_C 110_E 0.72 0.00
300_S 2_S 0.71 0.00
233_S 87_I 0.71 0.00
229_A 112_S 0.71 0.00
255_I 93_L 0.71 0.00
30_D 186_S 0.71 0.00
277_A 99_S 0.71 0.00
31_L 36_P 0.71 0.00
267_I 197_I 0.71 0.00
150_Q 55_L 0.71 0.00
55_R 132_L 0.71 0.00
55_R 55_L 0.71 0.00
47_V 169_E 0.70 0.00
142_A 211_L 0.70 0.00
261_E 141_I 0.70 0.00
187_T 177_R 0.70 0.00
49_A 84_Y 0.70 0.00
122_C 183_V 0.70 0.00
39_E 20_R 0.70 0.00
76_V 112_S 0.69 0.00
166_A 111_I 0.69 0.00
171_Q 6_T 0.69 0.00
81_I 152_V 0.69 0.00
206_E 112_S 0.69 0.00
218_S 87_I 0.68 0.00
245_M 106_P 0.68 0.00
178_A 101_Q 0.68 0.00
279_I 214_V 0.68 0.00
288_I 50_L 0.68 0.00
243_C 233_A 0.68 0.00
193_S 213_V 0.68 0.00
155_A 143_D 0.68 0.00
83_H 107_Q 0.68 0.00
224_M 53_S 0.68 0.00
103_S 65_A 0.68 0.00
122_C 4_L 0.67 0.00
94_R 105_Y 0.67 0.00
48_E 17_S 0.67 0.00
208_A 217_R 0.67 0.00
212_L 218_L 0.67 0.00
117_S 133_R 0.67 0.00
177_Q 26_A 0.67 0.00
6_Q 94_A 0.67 0.00
316_D 19_L 0.67 0.00
14_S 56_L 0.67 0.00
66_E 97_T 0.66 0.00
251_A 2_S 0.66 0.00
206_E 245_L 0.66 0.00
129_H 215_S 0.66 0.00
129_H 218_L 0.66 0.00
268_G 134_G 0.66 0.00
284_L 242_L 0.66 0.00
114_I 116_L 0.66 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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