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OPENSEQ.org

DHSA - DHSB
UniProt: P0AC41 - P07014
Length: 826
Sequences: 910
Seq/Len: 1.11
I_Prob: 0.10

DHSA - Succinate dehydrogenase flavoprotein subunit
Paralog alert: 0.67 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DHSA FRDA NADB
DHSB - Succinate dehydrogenase iron-sulfur subunit
Paralog alert: 0.40 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DHSB FRDB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2wdqAEI:BJFContact Map
2bs2AD:BEContact Map
2h88AN:BOContact Map
1kf6AM:BNContact Map
2gagB:A:AContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
325_S 141_E 1.58 0.10
446_R 91_I 1.34 0.05
326_R 215_V 1.23 0.04
249_A 31_R 1.16 0.03
524_Y 25_L 1.16 0.03
38_K 52_R 1.14 0.03
285_G 79_I 1.12 0.03
193_F 101_R 1.07 0.02
3_L 79_I 1.06 0.02
545_F 120_Y 1.04 0.02
113_R 134_L 1.01 0.02
508_T 50_S 0.99 0.02
199_V 49_L 0.99 0.02
163_E 52_R 0.99 0.02
449_N 91_I 0.99 0.02
254_T 59_V 0.99 0.02
154_L 120_Y 0.98 0.01
104_L 120_Y 0.98 0.01
239_W 1_M 0.98 0.01
482_K 83_N 0.97 0.01
341_D 116_K 0.97 0.01
23_A 215_V 0.97 0.01
442_D 91_I 0.96 0.01
446_R 29_E 0.95 0.01
209_Y 44_E 0.95 0.01
292_S 49_L 0.94 0.01
497_A 213_V 0.94 0.01
497_A 200_A 0.93 0.01
318_L 101_R 0.93 0.01
24_L 79_I 0.92 0.01
97_L 131_R 0.92 0.01
503_S 101_R 0.92 0.01
360_I 158_S 0.91 0.01
209_Y 141_E 0.91 0.01
490_I 29_E 0.90 0.01
447_W 11_N 0.90 0.01
508_T 70_K 0.89 0.01
583_P 91_I 0.89 0.01
189_E 171_G 0.89 0.01
332_E 81_A 0.88 0.01
20_M 7_I 0.88 0.01
385_A 211_N 0.88 0.01
336_T 78_P 0.88 0.01
325_S 137_P 0.88 0.01
504_S 17_A 0.87 0.01
546_P 89_I 0.87 0.01
337_F 218_K 0.87 0.01
207_R 56_R 0.87 0.01
96_I 218_K 0.86 0.01
416_G 90_V 0.86 0.01
478_D 27_A 0.85 0.01
499_L 47_P 0.84 0.01
209_Y 171_G 0.84 0.01
190_V 101_R 0.84 0.01
459_I 118_K 0.84 0.01
201_A 23_Y 0.83 0.01
495_K 5_F 0.83 0.01
329_G 57_E 0.83 0.01
506_F 104_V 0.83 0.01
32_T 17_A 0.83 0.01
37_S 233_L 0.82 0.01
487_L 45_K 0.82 0.01
505_E 11_N 0.82 0.01
334_S 42_L 0.82 0.01
214_N 105_V 0.82 0.01
174_D 117_I 0.82 0.01
45_H 193_R 0.82 0.01
438_E 15_D 0.81 0.01
508_T 136_M 0.81 0.01
434_E 91_I 0.81 0.01
202_T 13_D 0.81 0.01
226_A 77_T 0.81 0.01
326_R 78_P 0.80 0.01
145_L 202_S 0.80 0.01
551_E 16_D 0.80 0.01
238_M 120_Y 0.80 0.01
320_K 91_I 0.80 0.01
73_V 25_L 0.80 0.01
364_V 86_G 0.79 0.01
362_T 12_P 0.79 0.01
47_V 57_E 0.79 0.01
65_W 171_G 0.78 0.01
197_A 104_V 0.78 0.01
459_I 67_M 0.78 0.01
154_L 115_E 0.78 0.01
508_T 43_K 0.78 0.01
471_F 188_T 0.78 0.01
50_Q 57_E 0.78 0.01
195_A 29_E 0.78 0.01
479_A 202_S 0.78 0.01
369_L 22_D 0.77 0.01
534_T 139_Q 0.76 0.01
184_C 174_G 0.76 0.01
499_L 14_V 0.76 0.01
146_L 218_K 0.76 0.01
529_S 35_L 0.76 0.01
326_R 201_F 0.75 0.01
336_T 76_I 0.75 0.01
416_G 202_S 0.75 0.01
209_Y 15_D 0.75 0.01
490_I 64_G 0.75 0.01
516_L 196_G 0.75 0.01
421_E 4_E 0.75 0.01
35_L 66_N 0.75 0.01
83_D 222_P 0.75 0.01
96_I 65_L 0.75 0.01
42_T 151_L 0.74 0.01
416_G 110_F 0.74 0.01
10_A 17_A 0.74 0.01
582_P 90_V 0.74 0.01
332_E 160_P 0.74 0.01
566_M 64_G 0.74 0.01
145_L 130_A 0.74 0.01
196_R 215_V 0.74 0.01
176_A 14_V 0.74 0.01
151_Q 133_H 0.74 0.01
456_P 6_S 0.73 0.01
445_N 11_N 0.73 0.01
138_A 180_R 0.73 0.01
453_G 4_E 0.73 0.01
273_M 161_S 0.73 0.01
416_G 162_F 0.73 0.01
238_M 62_S 0.73 0.01
257_C 174_G 0.73 0.01
115_Y 222_P 0.73 0.01
254_T 18_P 0.73 0.01
89_C 79_I 0.73 0.01
504_S 11_N 0.73 0.01
585_I 81_A 0.73 0.01
227_I 233_L 0.72 0.01
182_A 49_L 0.72 0.01
427_G 117_I 0.72 0.01
229_A 99_V 0.72 0.01
186_E 100_I 0.72 0.01
435_S 188_T 0.72 0.01
323_L 7_I 0.72 0.01
332_E 218_K 0.72 0.01
553_W 25_L 0.72 0.01
326_R 62_S 0.72 0.01
110_D 24_T 0.72 0.01
434_E 100_I 0.72 0.01
32_T 124_N 0.72 0.01
76_S 117_I 0.72 0.01
201_A 139_Q 0.71 0.01
48_S 59_V 0.71 0.01
451_R 235_Q 0.71 0.01
18_A 227_G 0.71 0.01
165_Y 203_V 0.71 0.01
385_A 138_E 0.71 0.01
187_T 142_K 0.71 0.01
433_S 64_G 0.71 0.01
93_P 47_P 0.71 0.01
169_L 99_V 0.71 0.01
492_E 142_K 0.71 0.01
422_S 91_I 0.70 0.01
314_K 76_I 0.70 0.01
187_T 22_D 0.70 0.01
269_G 7_I 0.70 0.01
520_M 45_K 0.70 0.01
306_P 64_G 0.70 0.01
212_T 105_V 0.70 0.01
301_R 188_T 0.70 0.01
342_P 105_V 0.70 0.01
527_A 191_D 0.70 0.01
344_K 22_D 0.70 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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