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OPENSEQ.org

EPMA - SYH
UniProt: P0A8N7 - P60906
Length: 749
Sequences: 582
Seq/Len: 0.81
I_Prob: 0.00

EPMA - Elongation factor P--(R)-beta-lysine ligase
Paralog alert: 0.93 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: EPMA SYD SYK1 SYK2 SYN
SYH - Histidine--tRNA ligase
Paralog alert: 0.25 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: SYH
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2rhqA:A:BContact Map
3pcoAC:AC:BDContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
261_R 276_L 1.37 0.00
14_P 393_A 1.28 0.00
287_L 119_K 1.22 0.00
22_I 289_D 1.18 0.00
257_E 404_S 1.11 0.00
93_F 184_F 1.10 0.00
149_Y 334_V 1.08 0.00
168_Q 399_V 1.06 0.00
224_Q 19_T 1.06 0.00
97_R 275_S 1.05 0.00
97_R 34_G 1.02 0.00
305_V 333_L 1.01 0.00
156_Y 165_L 1.01 0.00
30_F 110_P 0.99 0.00
125_Y 347_L 0.99 0.00
147_L 347_L 0.96 0.00
295_S 240_L 0.95 0.00
79_Y 225_L 0.95 0.00
257_E 124_Q 0.94 0.00
245_L 180_A 0.94 0.00
255_A 62_V 0.94 0.00
275_P 387_L 0.93 0.00
275_P 165_L 0.93 0.00
38_V 31_N 0.90 0.00
230_H 357_G 0.89 0.00
260_Q 387_L 0.88 0.00
156_Y 339_D 0.88 0.00
166_K 25_I 0.87 0.00
263_E 252_T 0.87 0.00
17_L 309_L 0.87 0.00
262_F 143_E 0.86 0.00
213_Y 303_V 0.86 0.00
283_L 115_E 0.85 0.00
308_A 93_I 0.85 0.00
173_A 307_M 0.84 0.00
274_L 399_V 0.84 0.00
285_E 408_T 0.83 0.00
18_K 253_V 0.83 0.00
96_C 5_I 0.83 0.00
170_R 415_V 0.82 0.00
254_D 182_V 0.82 0.00
15_N 401_D 0.82 0.00
147_L 394_N 0.81 0.00
232_V 62_V 0.81 0.00
149_Y 56_I 0.81 0.00
91_P 217_A 0.81 0.00
147_L 252_T 0.80 0.00
131_V 401_D 0.80 0.00
262_F 79_T 0.80 0.00
213_Y 97_L 0.80 0.00
79_Y 413_D 0.80 0.00
312_E 225_L 0.80 0.00
314_L 184_F 0.80 0.00
37_E 106_W 0.79 0.00
316_E 362_T 0.79 0.00
140_D 360_L 0.79 0.00
29_F 75_G 0.79 0.00
30_F 302_A 0.79 0.00
34_G 18_E 0.79 0.00
273_G 344_A 0.79 0.00
158_E 32_V 0.78 0.00
131_V 19_T 0.78 0.00
68_G 246_S 0.78 0.00
156_Y 103_Q 0.78 0.00
291_M 151_W 0.78 0.00
32_D 154_A 0.78 0.00
22_I 358_V 0.78 0.00
178_L 28_T 0.78 0.00
179_S 374_A 0.78 0.00
261_R 95_H 0.78 0.00
89_C 320_N 0.78 0.00
60_F 210_S 0.78 0.00
316_E 150_R 0.78 0.00
277_H 295_L 0.77 0.00
63_P 56_I 0.77 0.00
87_A 161_V 0.77 0.00
309_L 135_L 0.77 0.00
175_K 378_K 0.77 0.00
123_D 235_E 0.77 0.00
26_I 25_I 0.77 0.00
136_Q 347_L 0.77 0.00
125_Y 321_P 0.77 0.00
221_S 418_H 0.76 0.00
142_P 231_E 0.76 0.00
261_R 56_I 0.76 0.00
238_V 251_Y 0.76 0.00
164_A 91_A 0.76 0.00
170_R 292_V 0.76 0.00
299_L 180_A 0.76 0.00
264_Q 282_V 0.76 0.00
254_D 119_K 0.75 0.00
316_E 222_A 0.75 0.00
117_W 164_E 0.75 0.00
166_K 186_E 0.75 0.00
90_G 160_H 0.75 0.00
125_Y 309_L 0.75 0.00
147_L 380_G 0.74 0.00
309_L 275_S 0.74 0.00
316_E 230_D 0.74 0.00
9_P 33_L 0.74 0.00
184_T 289_D 0.74 0.00
130_E 407_Q 0.74 0.00
213_Y 364_H 0.74 0.00
228_E 348_A 0.74 0.00
314_L 308_G 0.73 0.00
16_L 283_C 0.73 0.00
128_M 89_V 0.73 0.00
87_A 145_I 0.73 0.00
68_G 186_E 0.73 0.00
115_L 420_R 0.73 0.00
316_E 389_E 0.73 0.00
256_R 413_D 0.73 0.00
13_I 202_T 0.73 0.00
235_R 56_I 0.73 0.00
297_V 373_F 0.72 0.00
232_V 87_G 0.72 0.00
175_K 346_A 0.72 0.00
232_V 154_A 0.72 0.00
171_E 386_V 0.72 0.00
125_Y 378_K 0.72 0.00
99_F 347_L 0.72 0.00
174_A 17_G 0.72 0.00
56_F 15_L 0.72 0.00
299_L 368_N 0.72 0.00
87_A 239_G 0.71 0.00
106_R 79_T 0.71 0.00
182_A 25_I 0.71 0.00
17_L 105_L 0.71 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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