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OPENSEQ.org

SUCC - SUCD
UniProt: P0A836 - P0AGE9
Length: 677
Sequences: 817
Seq/Len: 1.21
I_Prob: 0.95

SUCC - Succinyl-CoA ligase [ADP-forming] subunit beta
Paralog alert: 0.12 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: SUCC
SUCD - Succinyl-CoA ligase [ADP-forming] subunit alpha
Paralog alert: 0.55 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: SUCD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3mwdA:BContact Map
2fp4B:A:BContact Map
2nu8BE:AD:BEContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
162_E 58_R 2.22 0.95
161_R 80_D 1.81 0.83
150_D 11_V 1.30 0.42
278_L 276_S 1.25 0.37
158_Y 80_D 1.19 0.31
158_Y 42_G 1.16 0.28
188_F 103_L 1.11 0.24
352_N 23_F 1.07 0.21
161_R 42_G 1.06 0.20
165_F 55_N 1.06 0.20
121_V 103_L 1.06 0.20
124_M 258_T 1.00 0.16
158_Y 83_L 0.99 0.15
113_V 203_A 0.98 0.15
278_L 141_H 0.97 0.14
57_A 271_V 0.96 0.14
47_C 119_M 0.96 0.13
279_H 72_Y 0.95 0.13
61_K 223_K 0.93 0.12
352_N 79_K 0.93 0.12
65_S 47_T 0.91 0.11
309_D 197_K 0.91 0.11
320_G 98_E 0.91 0.11
113_V 261_E 0.90 0.10
120_R 113_D 0.89 0.10
239_D 151_V 0.88 0.10
3_L 233_Y 0.88 0.10
323_V 274_V 0.88 0.09
158_Y 87_D 0.88 0.09
158_Y 111_K 0.88 0.09
221_N 99_G 0.87 0.09
150_D 70_V 0.87 0.09
24_A 202_E 0.87 0.09
132_E 110_V 0.86 0.09
91_Q 243_K 0.86 0.09
174_V 91_K 0.84 0.08
158_Y 55_N 0.83 0.08
306_L 227_T 0.83 0.07
225_R 104_D 0.83 0.07
119_R 106_L 0.83 0.07
259_I 150_I 0.81 0.07
165_F 80_D 0.81 0.07
375_T 279_D 0.81 0.07
120_R 110_V 0.81 0.07
384_A 276_S 0.81 0.07
138_E 269_A 0.81 0.07
157_P 80_D 0.80 0.07
291_G 155_G 0.79 0.06
179_K 287_V 0.78 0.06
138_E 205_V 0.78 0.06
361_L 56_T 0.78 0.06
89_N 243_K 0.78 0.06
11_L 288_L 0.78 0.06
266_A 245_M 0.78 0.06
139_E 286_T 0.78 0.06
322_I 24_H 0.77 0.06
152_L 110_V 0.77 0.06
226_Q 284_L 0.77 0.06
334_G 35_M 0.77 0.06
11_L 2_S 0.77 0.06
114_V 102_T 0.77 0.06
380_Q 197_K 0.77 0.06
319_F 24_H 0.77 0.06
226_Q 252_I 0.77 0.06
241_R 184_P 0.77 0.05
11_L 12_I 0.77 0.05
327_L 20_Q 0.77 0.05
322_I 96_I 0.76 0.05
27_T 56_T 0.76 0.05
57_A 251_I 0.76 0.05
190_E 183_I 0.76 0.05
251_N 77_F 0.75 0.05
138_E 94_I 0.75 0.05
106_K 276_S 0.75 0.05
80_R 183_I 0.75 0.05
180_I 183_I 0.75 0.05
116_R 96_I 0.74 0.05
162_E 87_D 0.74 0.05
377_A 12_I 0.74 0.05
275_I 278_A 0.74 0.05
100_A 5_I 0.74 0.05
363_D 113_D 0.73 0.05
237_Q 233_Y 0.73 0.05
355_E 287_V 0.73 0.04
186_T 89_G 0.73 0.04
180_I 46_T 0.73 0.04
189_L 103_L 0.73 0.04
96_I 288_L 0.73 0.04
221_N 182_P 0.72 0.04
153_T 110_V 0.72 0.04
159_Q 80_D 0.72 0.04
158_Y 40_T 0.72 0.04
360_K 29_I 0.72 0.04
374_L 165_T 0.72 0.04
135_K 200_Q 0.71 0.04
253_V 207_I 0.71 0.04
312_K 176_V 0.71 0.04
12_F 227_T 0.71 0.04
288_D 24_H 0.71 0.04
252_Y 43_K 0.71 0.04
193_L 81_S 0.70 0.04
72_F 34_K 0.70 0.04
359_K 148_V 0.70 0.04
156_M 55_N 0.70 0.04
380_Q 10_K 0.70 0.04
279_H 13_C 0.70 0.04
264_N 159_Y 0.69 0.04
66_K 282_E 0.69 0.04
84_Y 251_I 0.69 0.04
160_G 70_V 0.69 0.04
8_A 8_N 0.69 0.04
307_S 151_V 0.69 0.04
236_S 189_I 0.69 0.04
119_R 186_S 0.69 0.04
253_V 150_I 0.68 0.04
172_K 100_I 0.68 0.04
346_V 94_I 0.68 0.04
270_M 159_Y 0.68 0.03
162_E 8_N 0.68 0.03
105_A 193_E 0.68 0.03
128_E 6_D 0.68 0.03
110_L 40_T 0.68 0.03
162_E 131_G 0.68 0.03
251_N 150_I 0.68 0.03
374_L 44_G 0.68 0.03
263_V 125_P 0.68 0.03
189_L 83_L 0.67 0.03
121_V 106_L 0.67 0.03
138_E 230_V 0.67 0.03
262_M 281_G 0.67 0.03
37_K 287_V 0.67 0.03
132_E 35_M 0.67 0.03
175_Q 59_E 0.67 0.03
186_T 220_A 0.67 0.03
39_G 86_I 0.67 0.03
168_G 187_N 0.67 0.03
273_M 238_T 0.67 0.03
194_A 103_L 0.67 0.03
111_G 261_E 0.67 0.03
27_T 231_V 0.67 0.03
356_L 13_C 0.67 0.03
322_I 156_T 0.66 0.03
286_F 210_I 0.66 0.03
377_A 175_C 0.66 0.03
25_C 58_R 0.66 0.03
120_R 69_S 0.66 0.03
166_K 58_R 0.66 0.03
176_Q 174_T 0.66 0.03
47_C 40_T 0.66 0.03
92_P 233_Y 0.66 0.03
380_Q 168_Y 0.66 0.03
358_A 59_E 0.66 0.03
259_I 119_M 0.65 0.03
78_G 176_V 0.65 0.03
360_K 77_F 0.65 0.03
47_C 67_T 0.65 0.03
313_A 118_R 0.65 0.03
30_E 81_S 0.65 0.03
108_L 166_T 0.65 0.03
230_R 46_T 0.65 0.03
328_I 28_A 0.65 0.03
298_V 3_I 0.65 0.03
138_E 254_G 0.65 0.03
349_L 28_A 0.65 0.03
139_E 148_V 0.65 0.03
241_R 274_V 0.65 0.03
87_D 79_K 0.65 0.03
96_I 163_K 0.65 0.03
361_L 258_T 0.65 0.03
198_I 224_E 0.65 0.03
168_G 284_L 0.65 0.03
270_M 156_T 0.65 0.03
6_Y 199_P 0.64 0.03
103_D 47_T 0.64 0.03
56_K 257_G 0.64 0.03
185_A 277_L 0.64 0.03
15_Y 2_S 0.64 0.03
79_K 48_H 0.64 0.03
116_R 125_P 0.64 0.03
146_K 2_S 0.64 0.03
156_M 83_L 0.64 0.03
160_G 199_P 0.64 0.03
315_L 275_R 0.64 0.03
223_L 288_L 0.64 0.03
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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