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OPENSEQ.org

GCSH - GCST
UniProt: P0A6T9 - P27248
Length: 493
Sequences: 749
Seq/Len: 1.54
I_Prob: 0.00

GCSH - Glycine cleavage system H protein
Paralog alert: 0.14 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: GCSH
GCST - Aminomethyltransferase
Paralog alert: 0.58 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: GCST YGFZ
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2gagA:CContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
69_D 74_V 1.08 0.00
102_I 284_L 1.05 0.00
47_E 345_R 1.05 0.00
88_S 245_S 1.02 0.00
67_A 174_F 0.97 0.00
25_Y 33_Q 0.92 0.00
72_A 130_E 0.89 0.00
41_V 50_S 0.87 0.00
59_A 289_K 0.86 0.00
10_Y 359_N 0.85 0.00
72_A 312_I 0.85 0.00
47_E 326_A 0.84 0.00
64_V 77_L 0.84 0.00
90_E 242_E 0.84 0.00
94_S 127_Q 0.84 0.00
67_A 359_N 0.84 0.00
61_A 62_T 0.83 0.00
25_Y 125_I 0.83 0.00
68_S 112_V 0.83 0.00
91_L 292_L 0.83 0.00
100_G 129_A 0.83 0.00
109_D 322_G 0.82 0.00
69_D 312_I 0.82 0.00
34_Q 290_G 0.82 0.00
85_L 73_D 0.81 0.00
100_G 3_Q 0.81 0.00
112_E 125_I 0.81 0.00
49_G 344_N 0.81 0.00
42_F 6_P 0.79 0.00
17_L 42_T 0.79 0.00
67_A 217_K 0.79 0.00
102_I 24_W 0.79 0.00
42_F 132_F 0.78 0.00
102_I 326_A 0.78 0.00
125_L 136_I 0.77 0.00
66_A 121_D 0.77 0.00
79_V 245_S 0.77 0.00
96_P 6_P 0.77 0.00
59_A 171_M 0.77 0.00
34_Q 354_P 0.77 0.00
17_L 3_Q 0.77 0.00
79_V 111_L 0.76 0.00
94_S 297_P 0.76 0.00
60_V 19_V 0.74 0.00
91_L 73_D 0.74 0.00
40_M 281_L 0.74 0.00
42_F 351_V 0.74 0.00
70_I 96_I 0.74 0.00
61_A 57_L 0.74 0.00
96_P 136_I 0.74 0.00
42_F 129_A 0.73 0.00
41_V 343_R 0.73 0.00
59_A 357_V 0.72 0.00
10_Y 12_T 0.72 0.00
108_S 80_S 0.72 0.00
34_Q 72_N 0.72 0.00
34_Q 59_G 0.72 0.00
43_V 361_K 0.72 0.00
117_L 346_E 0.72 0.00
34_Q 124_W 0.72 0.00
95_E 322_G 0.72 0.00
92_V 322_G 0.71 0.00
64_V 111_L 0.71 0.00
36_L 71_A 0.71 0.00
47_E 57_L 0.71 0.00
81_V 145_I 0.71 0.00
75_S 116_A 0.70 0.00
8_L 5_T 0.70 0.00
70_I 38_H 0.70 0.00
121_A 5_T 0.70 0.00
50_A 219_C 0.70 0.00
79_V 351_V 0.70 0.00
102_I 294_N 0.70 0.00
50_A 17_R 0.70 0.00
25_Y 80_S 0.69 0.00
56_D 108_F 0.69 0.00
42_F 289_K 0.69 0.00
83_D 276_H 0.68 0.00
78_I 109_F 0.68 0.00
70_I 127_Q 0.68 0.00
54_A 74_V 0.68 0.00
40_M 340_V 0.68 0.00
5_P 77_L 0.68 0.00
90_E 67_R 0.68 0.00
50_A 308_H 0.68 0.00
36_L 22_H 0.68 0.00
44_D 57_L 0.67 0.00
8_L 328_A 0.67 0.00
95_E 65_F 0.67 0.00
42_F 335_G 0.67 0.00
64_V 121_D 0.67 0.00
40_M 115_S 0.67 0.00
77_E 22_H 0.67 0.00
10_Y 337_T 0.67 0.00
32_H 316_T 0.67 0.00
100_G 16_A 0.67 0.00
58_C 183_F 0.67 0.00
27_V 280_K 0.67 0.00
61_A 56_D 0.67 0.00
64_V 124_W 0.66 0.00
59_A 88_M 0.66 0.00
114_E 201_N 0.66 0.00
18_R 353_K 0.66 0.00
115_S 250_N 0.66 0.00
117_L 321_L 0.66 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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