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OPENSEQ.org

HEM3 - HEM4
UniProt: P06983 - P09126
Length: 559
Sequences: 933
Seq/Len: 1.70
I_Prob: 0.05

HEM3 - Porphobilinogen deaminase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM3
HEM4 - Uroporphyrinogen-III synthase
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: HEM4
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
66_L 222_A 1.34 0.05
247_G 174_W 1.13 0.03
18_W 138_R 1.09 0.03
241_G 215_S 1.07 0.02
196_V 187_G 1.00 0.02
235_N 59_L 0.97 0.02
192_S 90_T 0.87 0.01
247_G 130_L 0.87 0.01
9_A 137_G 0.82 0.01
41_M 222_A 0.82 0.01
116_L 97_T 0.82 0.01
72_E 152_V 0.81 0.01
247_G 208_H 0.81 0.01
235_N 215_S 0.79 0.01
241_G 218_L 0.79 0.01
187_L 20_R 0.79 0.01
209_D 215_S 0.78 0.01
201_V 215_S 0.77 0.01
70_L 82_P 0.77 0.01
43_T 185_T 0.77 0.01
99_C 132_L 0.77 0.01
7_R 53_S 0.77 0.01
208_D 84_Y 0.77 0.01
262_L 240_A 0.76 0.01
266_P 26_A 0.76 0.01
301_E 2_S 0.76 0.01
247_G 179_V 0.76 0.01
63_V 213_V 0.75 0.01
42_V 93_L 0.75 0.01
9_A 160_R 0.75 0.01
108_F 144_T 0.75 0.01
96_V 141_I 0.75 0.01
29_A 10_P 0.75 0.01
196_V 209_C 0.74 0.01
20_A 134_G 0.74 0.01
281_Q 45_D 0.74 0.01
6_L 154_F 0.74 0.01
249_Y 125_A 0.73 0.01
99_C 134_G 0.73 0.01
63_V 137_G 0.72 0.01
91_Q 151_E 0.72 0.01
168_I 123_N 0.71 0.01
246_I 104_L 0.71 0.01
103_D 19_L 0.71 0.01
99_C 160_R 0.70 0.01
21_H 132_L 0.70 0.01
67_E 6_T 0.70 0.01
87_V 137_G 0.70 0.01
168_I 230_I 0.70 0.01
6_L 114_V 0.70 0.01
158_K 113_E 0.70 0.01
228_V 116_L 0.69 0.01
144_I 3_I 0.69 0.01
138_E 12_G 0.69 0.01
136_L 146_T 0.69 0.01
238_L 236_A 0.69 0.01
48_I 225_L 0.69 0.01
286_M 178_E 0.69 0.01
261_A 28_H 0.68 0.01
221_H 41_P 0.68 0.01
168_I 120_E 0.68 0.01
163_E 72_H 0.68 0.01
246_I 156_E 0.68 0.01
177_L 14_E 0.68 0.01
283_A 4_L 0.67 0.01
167_I 110_E 0.67 0.01
188_P 212_L 0.67 0.01
6_L 162_A 0.67 0.01
197_G 30_P 0.67 0.01
184_R 65_A 0.67 0.01
129_S 118_L 0.67 0.01
279_A 199_Q 0.67 0.01
128_S 117_Q 0.67 0.01
294_L 112_S 0.67 0.01
257_I 114_V 0.67 0.01
220_N 192_Q 0.66 0.01
286_M 105_Y 0.66 0.01
282_D 128_R 0.66 0.01
152_V 182_V 0.66 0.01
281_Q 220_K 0.66 0.01
8_I 210_R 0.66 0.01
294_L 130_L 0.66 0.01
58_G 4_L 0.65 0.01
249_Y 50_L 0.65 0.01
23_V 68_Q 0.65 0.01
8_I 19_L 0.65 0.01
9_A 188_E 0.65 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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