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OPENSEQ.org

BTUC - BTUD
UniProt: P06609 - P06611
Length: 575
Sequences: 4843
Seq/Len: 9.05
I_Prob: 0.98

BTUC - Vitamin B12 import system permease protein BtuC
Paralog alert: 0.86 [within 20: 0.62] - ratio of genomes with paralogs
Cluster includes: BTUC FECC FECD FEPD FEPG
BTUD - Vitamin B12 import ATP-binding protein BtuD
Paralog alert: 0.94 [within 20: 0.85] - ratio of genomes with paralogs
Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2qi9AB:CDContact Map
4g1uAB:CDContact Map
2nq2AB:CDContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
219_I 44_A 1.90 0.98
223_Q 77_Y 0.89 0.43
224_L 99_H 0.87 0.41
219_I 49_M 0.79 0.31
220_S 139_A 0.73 0.24
270_T 88_T 0.69 0.20
216_L 93_Y 0.65 0.17
213_M 96_L 0.62 0.15
89_G 163_S 0.59 0.13
127_I 218_E 0.59 0.12
93_V 88_T 0.58 0.12
223_Q 49_M 0.53 0.09
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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