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OPENSEQ.org

ILVH - LEU3
UniProt: P00894 - P30125
Length: 526
Sequences: 369
Seq/Len: 0.71
I_Prob: 0.00

ILVH - Acetolactate synthase isozyme 3 small subunit
Paralog alert: 0.04 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: ILVH ILVN
LEU3 - 3-isopropylmalate dehydrogenase
Paralog alert: 0.65 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DMLA IDH LEU3
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
148_A 254_S 1.27 0.00
149_R 297_N 1.10 0.00
70_V 264_M 1.10 0.00
143_K 257_C 1.09 0.00
59_Q 300_A 1.09 0.00
154_G 76_V 1.06 0.00
150_S 229_A 1.04 0.00
54_E 212_I 1.04 0.00
158_G 272_L 1.03 0.00
27_G 177_R 1.03 0.00
133_A 121_C 1.02 0.00
71_L 169_R 1.01 0.00
148_A 279_L 1.01 0.00
43_L 258_A 1.00 0.00
143_K 244_L 0.99 0.00
136_A 105_F 0.99 0.00
110_G 283_A 0.98 0.00
97_G 355_I 0.97 0.00
11_N 274_E 0.97 0.00
118_S 19_V 0.96 0.00
34_T 294_N 0.96 0.00
1_M 58_P 0.96 0.00
125_A 326_I 0.96 0.00
118_S 359_V 0.96 0.00
76_L 264_M 0.95 0.00
121_T 350_E 0.95 0.00
154_G 244_L 0.94 0.00
142_A 257_C 0.94 0.00
43_L 295_I 0.93 0.00
39_D 245_C 0.93 0.00
82_V 132_F 0.92 0.00
38_T 289_D 0.91 0.00
60_I 293_K 0.91 0.00
139_R 266_M 0.91 0.00
86_I 284_G 0.91 0.00
46_M 101_H 0.90 0.00
108_F 190_V 0.90 0.00
23_F 8_A 0.89 0.00
60_I 254_S 0.89 0.00
136_A 168_H 0.89 0.00
101_V 326_I 0.89 0.00
41_P 188_H 0.89 0.00
54_E 181_E 0.89 0.00
132_D 63_E 0.89 0.00
28_Y 134_I 0.89 0.00
23_F 228_N 0.89 0.00
55_K 321_A 0.88 0.00
66_K 213_A 0.88 0.00
11_N 33_R 0.88 0.00
102_K 98_L 0.87 0.00
36_A 352_G 0.87 0.00
13_S 161_A 0.87 0.00
31_E 310_R 0.87 0.00
131_L 187_R 0.87 0.00
85_E 51_D 0.87 0.00
89_V 161_A 0.86 0.00
155_L 260_I 0.86 0.00
111_Q 302_I 0.86 0.00
6_S 182_S 0.86 0.00
19_V 114_Y 0.86 0.00
39_D 305_L 0.86 0.00
54_E 350_E 0.86 0.00
102_K 105_F 0.86 0.00
158_G 108_L 0.86 0.00
36_A 284_G 0.86 0.00
67_L 136_C 0.85 0.00
112_I 135_L 0.85 0.00
131_L 278_G 0.85 0.00
31_E 164_T 0.85 0.00
84_R 290_I 0.85 0.00
5_L 19_V 0.84 0.00
101_V 41_S 0.84 0.00
84_R 287_A 0.84 0.00
71_L 328_R 0.83 0.00
155_L 273_N 0.83 0.00
142_A 217_P 0.83 0.00
34_T 125_A 0.82 0.00
136_A 322_I 0.82 0.00
150_S 47_G 0.82 0.00
46_M 62_V 0.82 0.00
67_L 234_I 0.82 0.00
20_I 268_P 0.82 0.00
119_L 224_M 0.82 0.00
132_D 68_A 0.82 0.00
45_R 239_Q 0.81 0.00
18_R 319_A 0.81 0.00
142_A 35_A 0.81 0.00
72_R 6_H 0.81 0.00
123_Q 152_R 0.81 0.00
122_V 188_H 0.80 0.00
92_Q 322_I 0.80 0.00
11_N 228_N 0.80 0.00
24_S 176_A 0.80 0.00
12_E 260_I 0.80 0.00
21_G 233_L 0.80 0.00
23_F 180_F 0.80 0.00
8_L 272_L 0.80 0.00
17_S 165_E 0.79 0.00
63_Q 300_A 0.79 0.00
119_L 58_P 0.79 0.00
86_I 221_L 0.79 0.00
4_I 184_R 0.79 0.00
11_N 206_R 0.79 0.00
53_D 136_C 0.79 0.00
96_Y 155_S 0.79 0.00
110_G 20_M 0.78 0.00
49_Q 305_L 0.78 0.00
22_L 103_K 0.78 0.00
135_L 19_V 0.78 0.00
62_K 355_I 0.78 0.00
27_G 17_P 0.78 0.00
130_K 288_P 0.78 0.00
57_L 19_V 0.78 0.00
9_L 244_L 0.78 0.00
60_I 228_N 0.78 0.00
118_S 303_L 0.78 0.00
35_V 58_P 0.78 0.00
77_G 328_R 0.78 0.00
50_T 122_P 0.77 0.00
46_M 310_R 0.77 0.00
82_V 301_Q 0.77 0.00
54_E 320_C 0.77 0.00
6_S 8_A 0.77 0.00
38_T 80_K 0.77 0.00
144_I 211_E 0.77 0.00
46_M 181_E 0.77 0.00
60_I 11_P 0.77 0.00
121_T 168_H 0.76 0.00
156_S 161_A 0.76 0.00
46_M 102_F 0.76 0.00
142_A 98_L 0.76 0.00
80_A 244_L 0.76 0.00
24_S 221_L 0.75 0.00
3_R 73_F 0.75 0.00
113_I 172_I 0.75 0.00
62_K 300_A 0.75 0.00
37_P 168_H 0.75 0.00
86_I 301_Q 0.75 0.00
86_I 73_F 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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