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OPENSEQ.org
4HR7_A - 4HR7_B
PDB: 4HR7 Query Sequences:

 Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 605
Sequences: 905
Seq/Len: 1.51
I_Prob: 0.98
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
34_S 149_D 2.30 0.98
72_I 145_P 1.12 0.35
223_I 137_A 1.07 0.31
71_E 145_P 1.04 0.27
130_C 124_M 1.01 0.25
18_L 126_Q 0.99 0.23
354_I 65_A 0.95 0.20
17_I 60_N 0.94 0.19
198_V 143_G 0.92 0.17
398_A 3_I 0.91 0.17
384_M 6_I 0.90 0.16
49_V 145_P 0.89 0.15
321_L 144_Q 0.89 0.15
261_A 136_K 0.89 0.15
254_R 115_L 0.87 0.14
293_I 90_T 0.86 0.14
113_M 9_L 0.85 0.13
384_M 101_A 0.85 0.13
40_K 126_Q 0.84 0.12
86_S 19_S 0.83 0.12
311_E 85_S 0.82 0.11
250_P 135_V 0.82 0.11
414_I 109_V 0.82 0.11
100_F 29_S 0.82 0.11
167_R 23_I 0.81 0.11
207_P 90_T 0.81 0.10
219_Q 83_V 0.80 0.10
93_E 144_Q 0.80 0.10
69_A 145_P 0.80 0.10
315_I 23_I 0.80 0.10
353_K 50_A 0.79 0.10
18_L 21_L 0.79 0.10
75_A 127_I 0.79 0.10
74_G 98_D 0.78 0.10
368_E 107_Q 0.78 0.09
34_S 148_F 0.78 0.09
7_I 138_I 0.78 0.09
186_R 17_G 0.78 0.09
370_H 149_D 0.77 0.09
253_R 14_E 0.77 0.09
108_E 79_S 0.77 0.09
113_M 87_M 0.76 0.09
371_I 13_V 0.76 0.08
373_A 84_R 0.76 0.08
439_Y 123_M 0.75 0.08
15_L 145_P 0.75 0.08
158_I 144_Q 0.75 0.08
105_P 88_V 0.75 0.08
195_N 20_E 0.75 0.08
208_R 102_F 0.75 0.08
267_I 8_K 0.74 0.08
41_H 3_I 0.74 0.07
198_V 12_L 0.74 0.07
262_K 98_D 0.73 0.07
343_D 2_D 0.73 0.07
190_K 142_S 0.73 0.07
386_G 23_I 0.73 0.07
172_V 149_D 0.72 0.07
20_A 27_E 0.72 0.07
308_L 129_A 0.72 0.07
143_D 103_I 0.72 0.07
350_S 117_I 0.71 0.07
324_K 110_N 0.71 0.07
240_V 81_H 0.70 0.06
323_I 101_A 0.70 0.06
152_I 108_K 0.70 0.06
143_D 138_I 0.70 0.06
67_I 149_D 0.70 0.06
154_Y 91_F 0.70 0.06
4_K 133_G 0.70 0.06
143_D 69_S 0.69 0.06
391_Y 17_G 0.69 0.06
120_I 29_S 0.69 0.06
58_K 38_A 0.69 0.06
48_T 150_E 0.69 0.06
75_A 145_P 0.69 0.06
20_A 28_E 0.69 0.06
187_A 124_M 0.69 0.06
35_A 99_A 0.68 0.06
435_T 6_I 0.68 0.06
218_G 124_M 0.68 0.06
398_A 18_I 0.68 0.06
227_E 154_V 0.68 0.06
251_E 6_I 0.68 0.06
402_M 116_C 0.68 0.06
184_M 114_T 0.68 0.06
275_F 140_V 0.68 0.06
195_N 108_K 0.68 0.05
314_R 46_Q 0.68 0.05
267_I 142_S 0.67 0.05
47_E 133_G 0.67 0.05
384_M 34_R 0.67 0.05
181_S 124_M 0.67 0.05
47_E 155_I 0.67 0.05
31_V 57_A 0.67 0.05
262_K 75_A 0.67 0.05
440_L 23_I 0.67 0.05
421_Q 142_S 0.67 0.05
287_I 31_R 0.67 0.05
157_I 128_E 0.67 0.05
293_I 114_T 0.67 0.05
148_I 64_P 0.67 0.05
5_I 153_V 0.67 0.05
351_P 90_T 0.66 0.05
152_I 6_I 0.66 0.05
117_V 123_M 0.66 0.05
438_H 87_M 0.66 0.05
345_N 23_I 0.66 0.05
430_F 22_E 0.66 0.05
75_A 112_G 0.66 0.05
364_G 20_E 0.65 0.05
355_T 132_S 0.65 0.05
293_I 3_I 0.65 0.05
328_V 75_A 0.65 0.05
219_Q 94_T 0.65 0.05
293_I 91_F 0.65 0.05
304_T 22_E 0.65 0.05
169_M 145_P 0.65 0.05
44_L 88_V 0.65 0.05
377_V 130_D 0.65 0.05
398_A 143_G 0.65 0.04
373_A 114_T 0.65 0.04
411_I 67_V 0.65 0.04
191_A 102_F 0.65 0.04
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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