May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

2VPZ_A - 2VPZ_B
PDB: 2VPZ Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 927
Sequences: 676
Seq/Len: 0.77
I_Prob: 0.53
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
613_E 24_K 1.98 0.53
51_P 18_A 1.46 0.17
35_K 26_E 1.17 0.07
54_Q 134_T 1.08 0.05
221_L 76_Y 1.01 0.04
632_L 145_L 1.01 0.04
234_A 88_K 1.00 0.03
55_G 21_V 0.98 0.03
586_P 172_R 0.96 0.03
317_A 22_A 0.96 0.03
199_N 69_V 0.95 0.03
36_V 103_D 0.95 0.03
175_V 22_A 0.92 0.02
83_Y 130_A 0.92 0.02
488_P 94_G 0.91 0.02
231_L 40_E 0.90 0.02
297_A 86_D 0.89 0.02
278_I 5_A 0.89 0.02
50_C 90_C 0.89 0.02
50_C 70_C 0.89 0.02
254_T 4_Y 0.89 0.02
714_K 89_K 0.88 0.02
657_A 44_G 0.88 0.02
500_L 121_H 0.87 0.02
37_E 112_Y 0.87 0.02
222_P 47_P 0.86 0.02
628_K 146_E 0.86 0.02
503_E 68_P 0.85 0.02
50_C 96_C 0.84 0.02
229_T 69_V 0.84 0.02
58_Q 37_W 0.84 0.02
84_R 14_V 0.84 0.02
171_A 86_D 0.84 0.02
234_A 137_T 0.83 0.02
323_V 88_K 0.83 0.02
648_E 21_V 0.82 0.02
623_H 82_L 0.82 0.02
202_K 85_V 0.82 0.01
249_Y 156_L 0.82 0.01
106_Y 22_A 0.82 0.01
712_L 7_A 0.82 0.01
622_I 5_A 0.82 0.01
640_L 36_L 0.82 0.01
176_L 86_D 0.81 0.01
657_A 47_P 0.81 0.01
252_K 151_P 0.81 0.01
701_G 67_V 0.80 0.01
625_E 82_L 0.80 0.01
235_W 8_I 0.80 0.01
411_I 85_V 0.79 0.01
430_L 85_V 0.78 0.01
15_C 93_C 0.78 0.01
93_D 149_E 0.78 0.01
95_I 172_R 0.77 0.01
211_S 47_P 0.77 0.01
93_D 172_R 0.77 0.01
443_H 4_Y 0.77 0.01
622_I 22_A 0.77 0.01
610_V 25_M 0.77 0.01
254_T 156_L 0.77 0.01
270_E 145_L 0.77 0.01
479_A 27_N 0.76 0.01
116_H 55_P 0.76 0.01
110_A 103_D 0.76 0.01
231_L 172_R 0.76 0.01
712_L 82_L 0.76 0.01
283_I 86_D 0.75 0.01
610_V 21_V 0.75 0.01
638_V 152_V 0.75 0.01
610_V 132_V 0.75 0.01
496_L 88_K 0.75 0.01
653_V 86_D 0.74 0.01
87_T 172_R 0.74 0.01
33_V 130_A 0.74 0.01
449_V 12_L 0.74 0.01
690_L 5_A 0.74 0.01
403_I 176_F 0.73 0.01
394_P 178_L 0.73 0.01
151_A 121_H 0.73 0.01
102_I 175_L 0.73 0.01
21_R 132_V 0.73 0.01
105_K 150_S 0.72 0.01
446_W 88_K 0.72 0.01
540_K 48_N 0.72 0.01
412_N 102_Y 0.72 0.01
556_T 99_A 0.72 0.01
257_F 44_G 0.72 0.01
151_A 65_P 0.72 0.01
22_C 70_C 0.71 0.01
22_C 90_C 0.71 0.01
696_L 123_L 0.71 0.01
198_K 12_L 0.71 0.01
627_A 48_N 0.71 0.01
29_V 155_A 0.71 0.01
475_L 99_A 0.71 0.01
688_N 9_D 0.71 0.01
661_K 44_G 0.71 0.01
430_L 18_A 0.71 0.01
256_G 22_A 0.70 0.01
295_P 48_N 0.70 0.01
293_H 69_V 0.70 0.01
21_R 57_Q 0.70 0.01
22_C 96_C 0.70 0.01
280_A 18_A 0.70 0.01
172_R 145_L 0.70 0.01
478_P 20_A 0.70 0.01
572_G 79_K 0.70 0.01
561_I 149_E 0.70 0.01
100_L 63_N 0.69 0.01
396_I 73_G 0.69 0.01
100_L 89_K 0.69 0.01
219_R 140_R 0.69 0.01
198_K 170_G 0.69 0.01
443_H 64_P 0.69 0.01
70_L 156_L 0.69 0.01
500_L 137_T 0.69 0.01
199_N 118_F 0.69 0.01
144_C 93_C 0.69 0.01
248_E 62_E 0.69 0.01
295_P 126_G 0.69 0.01
701_G 18_A 0.69 0.01
714_K 47_P 0.68 0.01
429_N 46_Y 0.68 0.01
193_F 32_G 0.68 0.01
576_L 139_C 0.68 0.01
576_L 5_A 0.68 0.01
222_P 46_Y 0.68 0.01
160_I 143_G 0.68 0.01
484_F 111_G 0.68 0.01
527_E 3_R 0.68 0.01
53_G 93_C 0.68 0.01
242_E 79_K 0.67 0.01
386_T 34_F 0.67 0.01
713_E 82_L 0.67 0.01
50_C 93_C 0.67 0.01
624_K 3_R 0.67 0.01
653_V 28_E 0.67 0.01
31_N 86_D 0.67 0.01
266_D 154_K 0.67 0.01
123_F 88_K 0.67 0.01
635_G 171_T 0.67 0.01
194_A 137_T 0.67 0.01
412_N 118_F 0.67 0.01
73_V 128_V 0.67 0.01
407_F 138_Y 0.67 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.1426 seconds.