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OPENSEQ.org

1RM6_A - 1RM6_B
PDB: 1RM6 Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 1093
Sequences: 1604
Seq/Len: 1.52
I_Prob: 0.41
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
635_I 311_A 1.61 0.41
633_D 315_K 1.51 0.33
635_I 314_R 1.42 0.27
756_D 301_G 1.32 0.21
695_R 232_D 1.17 0.13
635_I 315_K 1.16 0.13
14_R 210_I 1.15 0.12
763_D 307_R 1.10 0.10
504_I 8_R 1.07 0.09
760_E 303_K 1.01 0.07
580_E 174_A 0.95 0.06
759_T 307_R 0.92 0.05
759_T 308_V 0.89 0.05
234_I 106_H 0.88 0.04
466_L 75_G 0.86 0.04
698_T 228_R 0.83 0.04
638_K 223_S 0.81 0.03
126_D 67_D 0.81 0.03
487_T 108_A 0.80 0.03
54_I 70_L 0.80 0.03
537_A 175_E 0.80 0.03
167_A 176_I 0.76 0.03
170_F 70_L 0.74 0.02
236_V 75_G 0.74 0.02
537_A 110_A 0.73 0.02
415_L 236_A 0.73 0.02
702_S 225_V 0.73 0.02
260_L 239_A 0.72 0.02
140_M 72_I 0.72 0.02
638_K 225_V 0.72 0.02
224_A 74_A 0.72 0.02
70_A 212_V 0.72 0.02
111_I 210_I 0.71 0.02
301_K 86_A 0.71 0.02
439_I 116_L 0.69 0.02
155_I 14_T 0.69 0.02
424_W 169_V 0.69 0.02
632_V 210_I 0.69 0.02
125_V 184_T 0.69 0.02
758_I 14_T 0.68 0.02
695_R 228_R 0.68 0.02
395_Q 293_N 0.68 0.02
23_K 115_N 0.68 0.02
193_L 78_L 0.67 0.02
504_I 68_G 0.67 0.02
628_V 53_L 0.67 0.02
750_D 309_L 0.67 0.02
430_K 93_A 0.67 0.02
701_E 232_D 0.66 0.02
413_E 27_T 0.66 0.02
493_A 267_P 0.66 0.02
54_I 104_P 0.66 0.02
69_I 212_V 0.66 0.02
669_M 305_R 0.66 0.02
346_R 111_T 0.66 0.02
413_E 106_H 0.66 0.02
643_K 51_V 0.65 0.02
216_P 170_L 0.65 0.01
30_Y 255_A 0.65 0.01
394_P 299_I 0.65 0.01
382_I 277_D 0.64 0.01
439_I 91_W 0.64 0.01
25_T 55_G 0.64 0.01
574_P 17_D 0.64 0.01
52_A 169_V 0.64 0.01
423_G 171_D 0.64 0.01
63_E 51_V 0.64 0.01
149_D 17_D 0.64 0.01
420_A 250_A 0.64 0.01
629_E 119_D 0.63 0.01
433_K 315_K 0.63 0.01
20_G 112_L 0.63 0.01
294_I 116_L 0.63 0.01
168_A 77_T 0.63 0.01
671_M 25_E 0.63 0.01
386_K 307_R 0.63 0.01
474_L 110_A 0.63 0.01
641_A 78_L 0.63 0.01
110_A 95_A 0.63 0.01
53_R 216_G 0.63 0.01
56_A 179_P 0.63 0.01
128_E 190_L 0.63 0.01
685_R 253_R 0.63 0.01
24_V 34_T 0.62 0.01
55_L 171_D 0.62 0.01
136_P 254_V 0.62 0.01
124_K 243_Q 0.62 0.01
625_A 108_A 0.62 0.01
128_E 21_A 0.62 0.01
259_G 72_I 0.62 0.01
132_A 320_L 0.62 0.01
120_L 74_A 0.62 0.01
27_K 303_K 0.62 0.01
53_R 68_G 0.61 0.01
632_V 186_P 0.61 0.01
421_A 72_I 0.61 0.01
520_S 22_L 0.61 0.01
359_G 256_I 0.61 0.01
690_N 42_R 0.61 0.01
671_M 276_W 0.61 0.01
395_Q 300_T 0.61 0.01
501_L 116_L 0.61 0.01
542_G 283_T 0.61 0.01
390_I 53_L 0.61 0.01
531_N 171_D 0.61 0.01
563_D 53_L 0.61 0.01
294_I 16_A 0.60 0.01
386_K 77_T 0.60 0.01
553_D 174_A 0.60 0.01
165_D 17_D 0.60 0.01
534_I 70_L 0.60 0.01
502_S 16_A 0.60 0.01
168_A 189_Q 0.60 0.01
230_D 186_P 0.60 0.01
110_A 12_P 0.60 0.01
32_A 87_I 0.60 0.01
390_I 173_R 0.60 0.01
218_Y 305_R 0.59 0.01
230_D 72_I 0.59 0.01
60_S 184_T 0.59 0.01
380_L 170_L 0.59 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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