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OPENSEQ.org

1IXR_A - 1IXR_C
PDB: 1IXR Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 443
Sequences: 829
Seq/Len: 1.88
I_Prob: 0.01
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
107_R 115_M 1.20 0.01
63_P 79_I 1.12 0.01
100_A 2_L 1.10 0.01
33_P 300_A 1.07 0.01
131_V 279_E 1.05 0.01
77_V 235_G 1.05 0.01
86_L 284_Y 1.04 0.01
101_L 172_G 1.03 0.01
123_I 173_V 1.03 0.01
57_L 70_I 1.03 0.01
115_V 192_I 1.02 0.01
83_K 58_L 1.02 0.01
110_T 134_R 1.01 0.01
46_V 138_I 1.01 0.01
33_P 291_L 0.99 0.01
113_S 120_G 0.97 0.01
84_V 129_R 0.96 0.01
49_H 40_F 0.95 0.01
19_L 254_L 0.94 0.01
119_L 117_I 0.94 0.01
9_V 217_A 0.94 0.01
20_L 160_H 0.94 0.01
103_E 196_S 0.93 0.01
22_G 223_T 0.93 0.01
80_V 115_M 0.91 0.01
65_E 21_R 0.91 0.01
48_T 180_L 0.90 0.01
125_L 110_M 0.89 0.01
79_G 72_K 0.89 0.01
36_Q 308_L 0.89 0.01
23_G 78_A 0.89 0.01
123_I 188_A 0.88 0.01
94_P 265_T 0.88 0.01
53_K 295_P 0.88 0.01
110_T 72_K 0.87 0.01
53_K 268_T 0.87 0.01
11_K 113_F 0.87 0.01
123_I 70_I 0.86 0.01
76_S 265_T 0.86 0.01
125_L 204_K 0.86 0.01
42_K 61_N 0.86 0.01
129_G 119_I 0.86 0.01
25_G 67_G 0.85 0.01
83_K 120_G 0.85 0.01
130_K 296_R 0.85 0.01
115_V 304_A 0.84 0.01
117_R 11_I 0.84 0.01
129_G 250_E 0.84 0.01
108_L 86_E 0.84 0.01
125_L 2_L 0.84 0.01
97_L 161_L 0.84 0.01
109_L 273_D 0.84 0.01
128_K 61_N 0.83 0.01
93_P 25_E 0.83 0.01
113_S 172_G 0.83 0.01
80_V 54_I 0.83 0.01
47_H 56_H 0.83 0.01
15_G 148_T 0.83 0.01
83_K 78_A 0.83 0.01
123_I 1_A 0.82 0.01
63_P 168_E 0.82 0.01
123_I 118_V 0.81 0.01
45_G 186_E 0.81 0.01
94_P 59_G 0.81 0.01
105_D 158_V 0.81 0.01
28_L 21_R 0.81 0.01
87_A 78_A 0.81 0.01
126_E 134_R 0.81 0.01
48_T 148_T 0.81 0.01
123_I 219_E 0.80 0.01
3_R 271_S 0.80 0.01
26_F 119_I 0.80 0.01
20_L 300_A 0.80 0.01
115_V 98_L 0.80 0.01
41_G 58_L 0.80 0.01
3_R 163_Y 0.80 0.01
86_L 117_I 0.80 0.01
126_E 122_G 0.79 0.01
21_A 241_L 0.79 0.01
50_L 64_V 0.79 0.00
111_S 25_E 0.79 0.00
108_L 11_I 0.78 0.00
83_K 105_H 0.78 0.00
112_A 114_V 0.78 0.00
22_G 291_L 0.78 0.00
34_F 176_D 0.78 0.00
119_L 172_G 0.78 0.00
68_L 256_F 0.78 0.00
12_K 284_Y 0.77 0.00
75_L 274_P 0.77 0.00
128_K 222_I 0.77 0.00
118_R 256_F 0.77 0.00
113_S 7_L 0.77 0.00
20_L 51_A 0.76 0.00
111_S 290_L 0.76 0.00
70_L 173_V 0.76 0.00
121_E 256_F 0.76 0.00
99_R 138_I 0.75 0.00
30_A 19_K 0.75 0.00
115_V 254_L 0.75 0.00
67_N 24_L 0.75 0.00
67_N 76_L 0.75 0.00
74_L 137_L 0.75 0.00
86_L 78_A 0.75 0.00
6_R 196_S 0.75 0.00
93_P 118_V 0.75 0.00
86_L 124_A 0.75 0.00
37_A 181_G 0.74 0.00
126_E 133_P 0.74 0.00
30_A 149_A 0.74 0.00
100_A 63_R 0.74 0.00
104_G 250_E 0.74 0.00
97_L 146_L 0.74 0.00
51_L 19_K 0.74 0.00
111_S 64_V 0.74 0.00
30_A 146_L 0.73 0.00
64_D 18_Q 0.73 0.00
64_D 178_R 0.73 0.00
10_L 70_I 0.72 0.00
24_V 22_V 0.72 0.00
52_L 267_A 0.72 0.00
38_L 206_L 0.72 0.00
95_R 223_T 0.72 0.00
30_A 255_R 0.72 0.00
34_F 37_L 0.72 0.00
87_A 87_G 0.72 0.00
106_A 158_V 0.72 0.00
38_L 192_I 0.72 0.00
130_K 159_E 0.72 0.00
125_L 263_L 0.72 0.00
44_V 6_T 0.71 0.00
128_K 49_T 0.71 0.00
108_L 2_L 0.71 0.00
42_K 21_R 0.71 0.00
45_G 184_I 0.71 0.00
121_E 118_V 0.71 0.00
22_G 188_A 0.70 0.00
123_I 14_E 0.70 0.00
8_L 196_S 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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