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OPENSEQ.org

1EFP_A - 1EFP_B
PDB: 1EFP Query Sequences:

Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.
Length: 560
Sequences: 1347
Seq/Len: 2.46
I_Prob: 1.00
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
176_S 171_A 3.97 1.00
307_K 240_D 3.72 1.00
137_K 220_E 3.07 1.00
101_R 137_A 2.39 0.99
105_L 137_A 2.36 0.99
180_D 168_Q 1.95 0.97
110_V 130_A 1.67 0.93
275_V 242_L 1.64 0.92
174_L 142_A 1.60 0.91
139_K 220_E 1.59 0.91
101_R 143_Q 1.57 0.90
179_A 169_T 1.52 0.88
124_E 225_R 1.49 0.87
135_V 223_S 1.46 0.86
174_L 140_G 1.43 0.84
107_D 103_K 1.37 0.81
104_A 134_M 1.36 0.80
174_L 173_S 1.23 0.69
293_L 236_V 1.18 0.65
307_K 243_V 1.16 0.62
178_V 171_A 1.13 0.59
291_Y 242_L 1.07 0.53
70_A 143_Q 1.06 0.51
137_K 222_V 1.04 0.48
105_L 140_G 1.01 0.46
178_V 169_T 0.97 0.40
292_G 198_A 0.95 0.38
303_E 239_V 0.91 0.33
176_S 173_S 0.90 0.32
178_V 158_K 0.88 0.29
109_M 219_L 0.87 0.29
104_A 138_I 0.86 0.28
293_L 239_V 0.84 0.26
109_M 97_E 0.84 0.26
140_D 218_R 0.83 0.24
136_V 219_L 0.82 0.24
198_S 86_V 0.82 0.23
40_S 58_I 0.81 0.23
148_R 36_N 0.81 0.23
176_S 156_K 0.81 0.22
291_Y 249_A 0.79 0.21
274_I 230_R 0.79 0.21
132_A 224_V 0.79 0.21
295_G 238_S 0.78 0.20
112_S 128_M 0.76 0.18
228_A 233_G 0.76 0.18
29_L 221_V 0.75 0.18
56_K 149_K 0.75 0.17
134_Q 224_V 0.74 0.17
227_R 44_E 0.74 0.17
244_T 233_G 0.74 0.16
8_E 166_G 0.74 0.16
304_L 243_V 0.73 0.16
100_P 144_A 0.73 0.15
99_M 238_S 0.73 0.15
206_K 3_V 0.73 0.15
188_P 164_D 0.73 0.15
281_E 235_K 0.72 0.15
177_W 172_V 0.72 0.15
75_A 140_G 0.71 0.14
292_G 235_K 0.71 0.14
100_P 129_N 0.71 0.14
275_V 205_E 0.70 0.14
97_N 145_T 0.70 0.14
160_T 106_A 0.70 0.13
153_D 251_V 0.70 0.13
98_V 152_I 0.69 0.13
181_E 169_T 0.69 0.13
110_V 128_M 0.68 0.12
154_A 200_K 0.68 0.12
111_L 221_V 0.67 0.12
293_L 105_L 0.67 0.12
27_K 156_K 0.67 0.12
22_A 23_G 0.67 0.11
71_E 19_V 0.66 0.11
117_I 68_A 0.66 0.11
197_V 144_A 0.66 0.11
126_P 127_D 0.66 0.11
142_K 97_E 0.66 0.11
294_V 139_L 0.66 0.11
152_F 162_E 0.65 0.11
224_G 38_F 0.65 0.11
196_V 118_I 0.65 0.11
184_E 65_V 0.65 0.10
281_E 76_L 0.65 0.10
156_G 244_G 0.64 0.10
135_V 222_V 0.64 0.10
22_A 88_A 0.64 0.10
287_Q 190_A 0.64 0.10
230_V 127_D 0.64 0.10
258_I 144_A 0.63 0.10
90_P 208_A 0.63 0.09
128_Y 126_N 0.63 0.09
43_A 173_S 0.63 0.09
308_L 243_V 0.63 0.09
237_N 196_M 0.63 0.09
163_V 155_A 0.62 0.09
197_V 3_V 0.62 0.09
120_A 157_A 0.62 0.09
293_L 241_E 0.62 0.09
156_G 178_V 0.62 0.09
56_K 156_K 0.62 0.09
128_Y 25_G 0.62 0.09
23_V 76_L 0.61 0.09
116_A 240_D 0.61 0.09
26_V 96_I 0.61 0.08
186_D 209_A 0.61 0.08
281_E 168_Q 0.61 0.08
3_V 177_V 0.61 0.08
28_A 86_V 0.61 0.08
279_K 233_G 0.61 0.08
244_T 78_M 0.60 0.08
87_I 17_A 0.60 0.08
17_D 251_V 0.60 0.08
295_G 237_G 0.60 0.08
222_A 61_V 0.60 0.08
143_K 218_R 0.60 0.08
291_Y 250_G 0.60 0.08
286_F 198_A 0.60 0.08
102_V 108_V 0.60 0.08
36_C 236_V 0.59 0.08
183_A 166_G 0.59 0.08
139_K 218_R 0.59 0.08
92_T 58_I 0.59 0.08
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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